产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
| 1:50 - 1:200 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品属性
形式
Liquid
存储溶液
PBS, 50% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
Batch dependent (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 165-494 of human UGDH (NP_003350.1).
纯化方式
Purified by affinity chromatography
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
UDP-glucose 6-dehydrogenase , GDH , UDP-GlcDH , UDPGDH , UGD
功能与背景
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
数据库
研究领域
產品图片
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GTX32948 IHC-P Image
IHC-P analysis of rat brain tissue using GTX32948 UGDH antibody.
Dilution : 1:100
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GTX32948 ICC/IF Image
ICC/IF analysis of HeLa cells using GTX32948 UGDH antibody.
Blue : DAPI
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GTX32948 WB Image
WB analysis of various sample lysates using GTX32948 UGDH antibody.
Dilution : 1:1000
Loading : 25μg per lane
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GTX32948 IHC-P Image
IHC-P analysis of human liver cancer tissue using GTX32948 UGDH antibody.
Dilution : 1:100
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