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UPK1A抗体 [MSVA-735M] HistoMAX™

Orthogonal HistoMAX
Anti-UPK1A antibody [MSVA-735M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04462
Anti-UPK1A antibody [MSVA-735M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04462
Anti-UPK1A antibody [MSVA-735M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04462

目录号 GTX04462

宿主

 Mouse

克隆

 Monoclonal

克隆编号

 MSVA-735M

同种型

 IgG2b

实验应用

 IHC-P

种属反应

 Human
产品包装
500 μl (¥8900),
100 μl (¥4200)
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产品说明

摘要

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

29 kDa. ( Note )

阳性对照

Urinary bladder: A strong membranous and cytoplasmic Upk1a immunostaining should be seen in the urothelium (the staining can be limited to the top 1/3 or 2/3 of the urothelium).

Negative Control

Colon: Upk1a immunostaining should be absent in all cells of the colon mucosa.

产品属性

形式

Liquid

存储溶液

PBS, 0.05% BSA (Please contact us for PBS only format)

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein

纯化方式

Protein A/G purified

偶联

Unconjugated

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

uroplakin 1A , TSPAN21 , UP1A , UPIA , UPKA

细胞定位

Membrane; Multi-pass membrane protein

功能与背景

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

数据库

研究领域

產品图片

Anti-UPK1A antibody [MSVA-735M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04462

GTX04462 IHC-P Image

IHC-P analysis of human urinary bladder urothelium tissue section using GTX04462 UPK1A antibody [MSVA-735M] HistoMAX™.
Strong UPK1A immunostaining of the urothelium.

Anti-UPK1A antibody [MSVA-735M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04462

GTX04462 IHC-P Image

IHC-P analysis of human kidney Invasive urothelial carcinoma tissue section using GTX04462 UPK1A antibody [MSVA-735M] HistoMAX™.
Invasive urothelial carcinoma of the kidney pelvis with strong UPK1A positivity.

Anti-UPK1A antibody [MSVA-735M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04462

GTX04462 IHC-P Image

IHC-P analysis of human rectum mucosa tissue section using GTX04462 UPK1A antibody [MSVA-735M] HistoMAX™.
Complete absence of UPK1A immunostaining in rectal mucosa.

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产品包装 报价 (¥)
¥ 8900
¥ 4200
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