Vimentin抗体

Name: Vimentin抗体
Brand: GeneTex
SKU: GTX100619
Price: 4000.00 RMB
Rating: 4.8 (6 reviews)

Anti-Vimentin antibody used in Western Blot (WB). GTX100619

Anti-Vimentin antibody used in IHC (Paraffin sections) (IHC-P). GTX100619

Anti-Vimentin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX100619

Anti-Vimentin antibody used in ELISA (ELISA). GTX100619

Anti-Vimentin antibody used in Immunoprecipitation (IP). GTX100619

Anti-Vimentin antibody used in Immunohistochemistry (IHC). GTX100619

目录号 GTX100619

文献引用 127

宿主	Rabbit
克隆	Polyclonal
同种型	IgG
实验应用	WB, ICC/IF, IHC-P, IHC-Fr, IP, ELISA, IHC, Sandwich ELISA, IHC (Free Floating)
种属反应	Human, Mouse, Rat, Cat, Dog
产品包装	100 μl (¥4000), 25 μl (¥1700)

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View product citations for antibody GTX100619 on CiteAb

产品说明

摘要

Vimentin antibody detects vimentin, a type III intermediate filament protein with a predicted molecular weight of 54 kDa. Vimentin is highly expressed in cells of mesodermal origin as well as in some ectodermal cells, and is often used as a marker of mesenchymal stem cells. It is also utilized in combination with E-cadherin to study the morphological and phenotypic changes in cells undergoing epithelial–mesenchymal transition during development and tumor metastasis. In addition, vimentin antibody is a valuable reagent to stain neuronal precursors and developing radial glia cells.

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认

实验应用	稀释倍数
WB	1:5000-1:50000
ICC/IF	1:100-1:1000
IHC-P	1:100-1:1000
IHC-Fr	Assay dependent
IP	1:100-1:500
ELISA	Assay dependent
IHC	Assay dependent
Sandwich ELISA	Assay dependent
IHC (Free Floating)	Assay dependent
Note : Sandwich ELISA Capture : GTX629743 / GTX629744, Detection : GTX100619

WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

54 kDa. ( Note )

Observed MW

56 kDa. The observed M.W. is based on the following publication. PMID: 23185433 and 24926698

阳性对照

293T

预测种属反应

Bovine, Chicken, Guinea pig, Xenopus tropicalis, Chimpanzee(>80% identity)

产品属性

形式

Liquid

存储溶液

PBS, 20% Glycerol

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

1.14 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Recombinant protein encompassing a sequence within the center region of human Vimentin. The exact sequence is proprietary.

纯化方式

Purified by antigen-affinity chromatography.

偶联

Unconjugated

RRID

AB_1952557

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

别名

vimentin

功能与背景

Along with the microfilaments (actins) and microtubules (tubulins), the intermediate filaments represent a third class of well-characterized cytoskeletal elements. The subunits display a tissue-specific pattern of expression. Desmin (MIM 125660) is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue.[supplied by OMIM]

数据库

Gene ID: 7431 VIM
UniProt: P08670 VIM

研究领域

產品图片

GTX100619 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Vimentin antibody (GTX100619) diluted at 1:20000.

GTX100619 WB Image

Wild-type (WT) and Vimentin knockout (KO) 293T cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Vimentin antibody (GTX100619) diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX100619 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membranes were blotted with Vimentin antibody (GTX100619) diluted at 1:5000 and competitor's antibody diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

*The competitor is not affiliated with GeneTex and does not endorse this product.

GTX100619 IHC-P Image

Vimentin antibody detects Vimentin protein expression by immunohistochemical analysis.
Sample:Paraffin-Embedded adult mouse retina.
Green: Vimentin protein stained by Vimentin antibody (GTX100619) diluted at 1:250.
Red: beta Tubulin 3/ TUJ1, stained by beta Tubulin 3/ TUJ1 antibody [GT11710] (GTX631836) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

GTX100619 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Vimentin antibody (GTX100619) diluted at 1:50000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

GTX100619 IHC-P Image

Vimentin antibody detects Vimentin protein at cell membrane and cytoplasm in rat ovary by immunohistochemical analysis.
Sample: Paraffin-embedded rat ovary.
Vimentin antibody (GTX100619) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX100619 IHC-P Image

Vimentin antibody detects Vimentin protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse colon.
Vimentin stained by Vimentin antibody (GTX100619) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX100619 IHC-P Image

Vimentin antibody detects Vimentin protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse intestine.
Vimentin stained by Vimentin antibody (GTX100619) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX100619 IHC-P Image

Vimentin antibody detects Vimentin protein at cell membrane and cytoplasm in rat testis by immunohistochemical analysis.
Sample: Paraffin-embedded rat testis.
Vimentin antibody (GTX100619) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX100619 IHC-P Image

Vimentin antibody detects Vimentin protein at cytoplasm in human lung adenocarcinoma by immunohistochemical analysis.
Sample: Paraffin-embedded human lung adenocarcinoma.
Vimentin antibody (GTX100619) diluted at 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX100619 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (10 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Vimentin antibody (GTX100619) diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX100619 IHC-P Image

Vimentin antibody detects Vimentin protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse testis.
Vimentin stained by Vimentin antibody (GTX100619) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15

GTX100619 IHC-P Image

Vimentin antibody detects Vimentin protein at cell membrane and cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded rat ovary.
Vimentin stained by Vimentin antibody (GTX100619) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX100619 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Vimentin antibody (GTX100619) diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX100619 WB Image

Various extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Vimentin antibody (GTX100619) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX100619 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Vimentin antibody (GTX100619) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX100619 IHC-P Image

Vimentin antibody detects Vimentin protein by immunohistochemical analysis.
Sample: Paraffin-embedded dog pancreas.
Vimentin stained by Vimentin antibody (GTX100619) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX100619 ICC/IF Image

Vimentin antibody detects Vimentin protein at cytoskeleton by immunofluorescent analysis.
Sample: MDCK cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: Vimentin stained by Vimentin antibody (GTX100619) diluted at 1:500.
Blue: Hoechst 33342 staining.
Scale bar= 10 μm.

GTX100619 WB Image

Vimentin antibody detects Vimentin protein by western blot analysis.
A. 20 μg 293T whole cell lysate/extract
B. 10 μg 293T whole cell lysate/extract
C. 5 μg 293T whole cell lysate/extract
D. 1 μg 293T whole cell lysate/extract
10% SDS-PAGE
Vimentin antibody (GTX100619) dilution: 1:10000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX100619 ELISA Image

Sandwich ELISA detection of recombinant full-length Vimentin protein using GTX629743 as capture antibody at concentration of 5 μg/mL and GTX100619 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX100619 WB Image

GTX100619 ELISA Image

Sandwich ELISA detection of recombinant full-length Vimentin protein using GTX629744 as capture antibody at concentration of 5 μg/mL and GTX100619 as detection antibody at concentration of 1 μg/mL. Rabbit IgG antibody (HRP) (GTX213110-01) was diluted at 1:10000 and used to detect the primary antibody.

GTX100619 IP Image

Immunoprecipitation of Vimentin protein from HeLa whole cell extracts using 5 μg of Vimentin antibody (GTX100619).
Western blot analysis was performed using Vimentin antibody (GTX100619).
EasyBlot anti-Rabbit IgG (GTX221666-01) was used as a secondary reagent.

GTX100619 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Vimentin antibody (GTX100619) diluted at 1:20000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX100619 ICC/IF Image

Vimentin antibody detects Vimentin protein at cytoskeleton and nucleus by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: Vimentin stained by Vimentin antibody (GTX100619) diluted at 1:500.
Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:1000.
Blue: Fluoroshield with DAPI (GTX30920).

GTX100619 WB Image

The data was published in the journal J Biomed Sci in 2016.PMID: 27863490

GTX100619 WB Image

The data was published in the journal J Biomed Sci in 2013. PMID: 24359494

GTX100619 WB Image

The data was published in the journal J Cell Mol Med in 2019. PMID: 30950191

GTX100619 WB Image

The data was published in the journal J Exp Clin Cancer Res in 2019. PMID: 31174567

GTX100619 WB Image

The data was published in the journal EMBO Rep in 2020. PMID: 31908141

GTX100619 WB Image

The data was published in the journal EMBO Rep in 2020. PMID: 31908141

GTX100619 WB Image

The data was published in the journal EMBO Rep in 2020. PMID: 31908141

GTX100619 WB Image

The data was published in the 2022 in J Biomed Sci. PMID: 35765067

GTX100619 IHC-P Image

The data was published in the journal PLoS One in 2014. PMID: 25397403

GTX100619 WB Image

The data was published in the journal Sci Rep in 2017. PMID: 28195146

GTX100619 WB Image

The data was published in the journal J Transl Med in 2017. PMID: 28472954

GTX100619 WB Image

The data was published in the journal Nat Commun in 2015. PMID: 26245647

GTX100619 WB Image

The data was published in the journal Nat Commun in 2015. PMID: 26245647

GTX100619 WB Image

The data was published in the journal J Transl Med in 2017. PMID: 28472954

GTX100619 IHC Image

The data was published in the journal Antioxidants (Basel) in 2020.PMID: 32218152

GTX100619 WB Image

The data was published in the journal Evid Based Complement Alternat Med in 2012.PMID: 23320038

GTX100619 WB Image

The data was published in the journal EMBO Rep in 2020. PMID: 31908141

GTX100619 WB Image

The data was published in the journal Oncotarget in 2014. PMID: 25237908

GTX100619 WB Image

The data was published in the journal Oncotarget in 2014. PMID: 25237908

GTX100619 WB Image

The data was published in the journal J Cell Mol Med in 2019. PMID: 30950191

GTX100619 WB Image

The data was published in the journal J Cell Mol Med in 2019. PMID: 30950191

GTX100619 ICC/IF Image

The data was published in the 2021 in Int J Mol Sci. PMID: 34281292

文献引用

Application Reference

B Xue et al. Sci Rep 2024; 14 (1) : 837 irculating exosomal miR-16-5p and let-7e-5p are associated with bladder fibrosis of diabetic cystopathy

实验应用 : ICC/IF

Kun W et al. J Tradit Chin Med 2023; 43 (5) : 944-954 Electroacupuncture ameliorates cardiac dysfunction in myocardial ischemia model rats: a potential role of the hypothalamic-pituitary-adrenal axis.

M Dahut et al. J Immunother Cancer 2023; 11 (9) : e007386 Fulvestrant increases the susceptibility of enzalutamide-resistant prostate cancer cells to NK-mediated lysis

实验应用 : WB, IHC-P

Y Zhang et al. Stem Cell Res 2023; : 103201 Human induced pluripotent stem cell line from fibroblasts (HEBHMUi015-A) and chondrogenic differentiation

实验应用 : ICC/IF

Yang KS et al. Sci Rep 2023; 13 (1) : 10969 Extracellular vesicle analysis of plasma allows differential diagnosis of atypical pancreatic serous cystadenoma.

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产品评论

Vimentin antibody 目录号 GTX100619

Rating

( Average 4.8 based on 6 users reviews)

实验应用

Western Blot(WB)		( Average 5 based on 4 users reviews)
Immunocytochemistry/ Immunofluorescence(ICC/IF)		( Average 4 based on 1 users reviews)
IHC (Free Floating)(IHC (Free Floating))		( Average 5 based on 1 users reviews)

Anti-Vimentin antibody used in IHC (Free Floating) (IHC (Free Floating)). GTX100619

Date : Anonymous submitted on 03-Oct-2023

Score :

Application Tested : IHC (Free Floating)

Sample Species : Ms

Sample : adult mouse brain tissue

Blocking : 1% BSA and 0.3% Triton X-100 in PBS, 25°C, 0.5Hr

Fixation : 4% PBS in PBS

Permeabilization /Antigen retrieval : 0.3% Triton X-100

Primary Antibody : 1:200, 4°C, >12Hr

Date : Anonymous submitted on 02-May-2023

Score :

Application Tested : WB

Sample Species : Hu

Sample : MDA-MB-231 cell lysates with/without treatment

Amount used : 40μg

Blocking : 5% non-fat milk in TBST, 25°C, 1Hr

Primary Antibody : 1:5000, 4°C, 16Hr

Date : Anonymous submitted on 19-Apr-2022

Score :

Application Tested : WB

Sample Species : Hu

Sample : HSC-3 cells with/without drug treatment

Amount used : 30μg

Blocking : 5% non-fat milk in TBST, 30°C, 1Hr

Primary Antibody : 1:1000, 4°C, 18Hr

Date : Anonymous submitted on 26-May-2018

Score :

Application Tested : WB

Sample Species : Hu

Amount used : 30 μg

Primary Antibody : 1:1000, 4°C, 16Hr

条带说明 : Lane 1: hFOB1.19 cells, Lane 2: MG63 cells, Lane 3: U2OS cells

Date : Anonymous submitted on 16-Nov-2017

Score :

Application Tested : ICC/IF

Sample Species : Hu

Sample : Dental pulp stem cells

Blocking : 5% NGS in 0.1% Triton-X in PBS, 25°C, 0.5Hr

Fixation : 4% PFA in PBS

Permeabilization /Antigen retrieval : 0.1% Triton-X in PBS

Primary Antibody : 1:1000, 4°C, 16Hr

Date : Anonymous submitted on 05-Nov-2014

Score :

Application Tested : WB

Sample Species : Hu

Sample : A549 cells

Amount used : 20μg

Blocking : 5% skim milk in TBST, 24°C, 1Hr

Primary Antibody : 1:50000, 4°C, 15Hr

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Application Reference

B Xue et al. Sci Rep 2024; 14 (1):837 irculating exosomal miR-16-5p and let-7e-5p are associated with bladder fibrosis of diabetic cystopathy

实验应用 : ICC/IF

Kun W et al. J Tradit Chin Med 2023; 43 (5):944-954 Electroacupuncture ameliorates cardiac dysfunction in myocardial ischemia model rats: a potential role of the hypothalamic-pituitary-adrenal axis.

M Dahut et al. J Immunother Cancer 2023; 11 (9):e007386 Fulvestrant increases the susceptibility of enzalutamide-resistant prostate cancer cells to NK-mediated lysis

实验应用 : WB, IHC-P

Y Zhang et al. Stem Cell Res 2023;:103201 Human induced pluripotent stem cell line from fibroblasts (HEBHMUi015-A) and chondrogenic differentiation

实验应用 : ICC/IF

Yang KS et al. Sci Rep 2023; 13 (1):10969 Extracellular vesicle analysis of plasma allows differential diagnosis of atypical pancreatic serous cystadenoma.

A Simiczyjew et al. Cell Mol Biol Lett 2023; 28 (1):58 Melanoma cells induce dedifferentiation and metabolic changes in adipocytes present in the tumor niche

实验应用 : WB

种属反应 : Human, Mouse

Mingjing Zhang et al. Stem Cell Research 2023; Human Induced pluripotent stem cell (iPSC) line (HEBHMUi014-A) derived from a patient with Alzheimer's disease

实验应用 : ICC/IF

种属反应 : Human

Sun C et al. Oncogenesis 2023; 12 (1):18 Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release.

实验应用 : WB

种属反应 : Mouse

Chang TM et al. Int J Biol Sci 2023; 19 (5):1455-1470 CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathway.

实验应用 : WB

种属反应 : Human

Su CC et al. Nutrients 2023; 15 (23) Protective Effect of Alpha-Linolenic Acid on Human Oral Squamous Cell Carcinoma Metastasis and Apoptotic Cell Death.

Taguchi K et al. J Clin Invest 2022; 132 (23) Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation.

实验应用 : WB, IHC-P

种属反应 : Mouse

Su MT et al. Pharmaceuticals (Basel) 2022; 15 (12) Aspirin Inhibits Fibronectin Expression and Reverses Fibronectin-Mediated Cell Invasiveness by Activating Akt Signaling in Preeclampsia.

He S et al. J Virol 2022; 96 (14):e0212721 PRRSV Infection Induces Gasdermin D-Driven Pyroptosis of Porcine Alveolar Macrophages through NLRP3 Inflammasome Activation.

Ni C et al. Nat Commun 2022; 13 (1):5919 ZIP1⁺ fibroblasts protect lung cancer against chemotherapy via connexin-43 mediated intercellular Zn²⁺ transfer.

实验应用 : WB

种属反应 : Mouse

Leung D et al. J Transl Med 2022; 20 (1):556 Platinum-resistance in epithelial ovarian cancer: an interplay of epithelial-mesenchymal transition interlinked with reprogrammed metabolism.

Wuputra K et al. Int J Mol Sci 2022; 23 (14) FOXM1-CD44 Signaling Is Critical for the Acquisition of Regorafenib Resistance in Human Liver Cancer Cells.

Matschke J et al. Front Neurol 2022; 13:908081 Young COVID-19 Patients Show a Higher Degree of Microglial Activation When Compared to Controls.

Wang L et al. Bioengineered 2022; 13 (5):12941-12954 Stearoyl-CoA desaturase 1 regulates malignant progression of cervical cancer cells.

Marlena Brzozowa-Zasada et al. Prz Gastroenterol 2022; 17 (2):123-129 Vimentin immunoexpression and its prognostic activity in colon cancer among Caucasian patients.

实验应用 : IHC-P

种属反应 : Human

Ching-Chung Ko et al. Int J Mol Sci 2022; 23 (12) Long Non-Coding RNA MIR31HG Promotes the Transforming Growth Factor β-Induced Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma Cells.

实验应用 : WB

种属反应 : Human

Jia-Huang Chen et al. J Biomed Sci 2022; 29 (1):46 The down-regulation of XBP1, an unfolded protein response effector, promotes acute kidney injury to chronic kidney disease transition.

实验应用 : WB

种属反应 : Mouse

Nastaran Mohammadi Ghahhari et al. Nat Commun 2022; 13 (1):2104 Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis.

Zou W et al. J Cell Mol Med 2022; siRNA-induced CD44 knockdown suppresses the proliferation and invasion of colorectal cancer stem cells through inhibiting epithelial-mesenchymal transition.

实验应用 : WB

种属反应 : Mouse

Pai JT et al. Int J Mol Sci 2022; 23 (3) Propolin G-Suppressed Epithelial-to-Mesenchymal Transition in Triple-Negative Breast Cancer Cells via Glycogen Synthase Kinase 3β-Mediated Snail and HDAC6-Regulated Vimentin Degradation.

实验应用 : WB

种属反应 : Human

Wojciech Snoch et al. Int J Mol Sci 2021; 22 (13) In Search of Effective Anticancer Agents-Novel Sugar Esters Based on Polyhydroxyalkanoate Monomers.

实验应用 : ICC/IF

种属反应 : Human

Li Xiao et al. Int J Mol Sci 2021; 22 (19) LEF1 Enhances the Progression of Colonic Adenocarcinoma via Remodeling the Cell Motility Associated Structures.

实验应用 : WB

种属反应 : Human

Kai-Wei Chang et al. Int J Mol Sci 2021; 22 (20) Atractylodin Suppresses TGF-β-Mediated Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells and Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice.

实验应用 : WB

种属反应 : Human

Chen YA et al. Sci Rep 2021; 11 (1):22430 Detection of cancer stem cells by EMT-specific biomarker-based peptide ligands.

实验应用 : WB

种属反应 : Human

Gaur G et al. Antibiotics (Basel) 2021; 10 (11) Effect of Invasion of Borrelia burgdorferi in Normal and Neoplastic Mammary Epithelial Cells.

实验应用 : WB

Kawami M et al. Toxicology 2021; 461:152903 Evaluation on epithelial-mesenchymal state and microRNAs focusing on isolated alveolar epithelial cells from bleomycin injured rat lung.

实验应用 : WB

种属反应 : Rat

Chen HH et al. iScience 2021; 24 (9):103086 DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation.

实验应用 : WB

种属反应 : Human

Lai YW et al. Cells 2021; 10 (8) Prognostic Value of a Glycolytic Signature and Its Regulation by Y-Box-Binding Protein 1 in Triple-Negative Breast Cancer.

实验应用 : WB

种属反应 : Human

Wang LT et al. Cancer Lett 2021; 520:160-171 Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance.

实验应用 : WB

种属反应 : Mouse

Wu TT et al. Antioxidants (Basel) 2021; 10 (7) 3H-1,2-Dithiole-3-Thione Protects Lens Epithelial Cells against Fructose-Induced Epithelial-Mesenchymal Transition via Activation of AMPK to Eliminate AKR1B1-Induced Oxidative Stress in Diabetes Mellitus.

实验应用 : WB

种属反应 : Rat

Wang Y et al. Nat Commun 2021; 12 (1):1736 The essential role of PRAK in tumor metastasis and its therapeutic potential.

实验应用 : WB

种属反应 : Mouse

Wang J et al. Cancer Manag Res 2021; 13:2701-2715 Circular RNA_0000629 Suppresses Bladder Cancer Progression Mediating MicroRNA-1290/CDC73.

实验应用 : WB

种属反应 : Human

Li Y et al. Transl Lung Cancer Res 2021; 10 (4):1841-1856 Let-7b-3p inhibits tumor growth and metastasis by targeting the BRF2-mediated MAPK/ERK pathway in human lung adenocarcinoma.

实验应用 : WB

种属反应 : Human

Hu W et al. JCI Insight 2021; 6 (3) NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma.

实验应用 : WB

种属反应 : Mouse

Chen HY et al. Antioxidants (Basel) 2021; 10 (1) Characterization of TGF-β by Induced Oxidative Stress in Human Trabecular Meshwork Cells.

实验应用 : WB

种属反应 : Human

Delgado-Valero B et al. Clin Sci (Lond) 2021; 135 (1):143-159 Role of endoplasmic reticulum stress in renal damage after myocardial infarction.

Bunker EN et al. Mol Biol Cell 2021; 32 (4):348-361 Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling.

Buqu? A et al. Nat Commun 2020; 11 (1):3819 Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer.

Klein M et al. Front Aging Neurosci 2020; 12:172 Age-Dependent Heterogeneity of Murine Olfactory Bulb Astrocytes.

Huang R et al. Ann Transl Med 2020; 8 (6):329 Restoration of TET2 deficiency inhibits tumor growth in head neck squamous cell carcinoma.

Zhang D et al. Oncol Rep 2020; 43 (4):1125-1132 Exosomes derived from Piwil2?induced cancer stem cells transform fibroblasts into cancer?associated fibroblasts.

Lee KY et al. Cells 2020; 10 (1) Upregulation of CD109 Promotes the Epithelial-to-Mesenchymal Transition and Stemness Properties of Lung Adenocarcinomas via Activation of the Hippo-YAP Signaling.

实验应用 : WB

种属反应 : Human

Wang JH et al. Cancers (Basel) 2020; 12 (11) The Long Noncoding RNA LOC441461 (STX17-AS1) Modulates Colorectal Cancer Cell Growth and Motility.

实验应用 : WB

种属反应 : Human

Kuo CH et al. Cell Biochem Funct 2020; (Epub) Biomarker discovery in highly invasive lung cancer cell through proteomics approaches.

实验应用 : WB

种属反应 : Human

Horn LA et al. J Immunother Cancer 2020; 8 (1) Simultaneous inhibition of CXCR1/2, TGF-β, and PD-L1 remodels the tumor and its microenvironment to drive antitumor immunity.

Ho KH et al. Cell Mol Neurobiol 2020; miR-4286 is Involved in Connections Between IGF-1 and TGF-β Signaling for the Mesenchymal Transition and Invasion by Glioblastomas.

实验应用 : WB

种属反应 : Human

Wang LT et al. EMBO Rep 2020; 21 (2):e48795 PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition.

Li CL et al. Anticancer Res 2020; 40 (10):5529-5538 Curcumol Suppresses Triple-negative Breast Cancer Metastasis by Attenuating Anoikis Resistance via Inhibition of Skp2-mediated Transcriptional Addiction.

实验应用 : WB

种属反应 : Human

Wang J et al. Onco Targets Ther 2020; 13:9333-9348

实验应用 : WB

种属反应 : Human

Li MK et al. Oncol Rep 2020; 44 (5):2130-2142 Long non?coding RNA MEG3 suppresses epithelial?to?mesenchymal transition by inhibiting the PSAT1?dependent GSK?3β/Snail signaling pathway in esophageal squamous cell carcinoma.

实验应用 : WB

种属反应 : Human

Duan L et al. Aging (Albany NY) 2020; 12 (16):16172-16182 Leptin promotes bone metastasis of breast cancer by activating the SDF-1/CXCR4 axis.

实验应用 : WB

种属反应 : Human

Huang HY et al. J Cell Mol Med 2020; Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis.

实验应用 : WB

种属反应 : Human

Navarrete-Bernal MGC et al. Front Oncol 2020; 10:1206 Biological Landscape of Triple Negative Breast Cancers Expressing CTLA-4.

实验应用 : WB

种属反应 : Human

Hsieh YH et al. Environ Toxicol 2020; 35 (9):1007-1014 Arecoline induces epithelial mesenchymal transition in HK2 cells by upregulating the ERK-mediated signaling pathway.

实验应用 : WB

种属反应 : Human

Chang YC et al. Front Cell Dev Biol 2020; 8:485 Tamoxifen Rechallenge Decreases Metastatic Potential but Increases Cell Viability and Clonogenicity in a Tamoxifen-Mediated Cytotoxicity-Resistant Subline of Human Breast MCF7 Cancer Cells.

实验应用 : WB

种属反应 : Human

Xiao L et al. Life Sci 2020; 253:117740 Roles of N-terminal Annexin A2 phosphorylation sites and miR-206 in colonic adenocarcinoma.

实验应用 : WB

种属反应 : Human

Wu TT et al. Antioxidants (Basel) 2020; 9 (4) AKR1B1-Induced Epithelial-Mesenchymal Transition Mediated by RAGE-Oxidative Stress in Diabetic Cataract Lens.

种属反应 : Human

Chen JF et al. J Pharm Biomed Anal 2020; 187:113142 Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells.

实验应用 : WB

种属反应 : Human

Dan Zhang et al. Oncology Reports 2020;:1125-1132 Exosomes derived from Piwil2?induced cancer stem cells transform fibroblasts into cancer?associated fibroblasts

实验应用 : WB

种属反应 : Human

Krutika Deshpande et al. Curr Protoc Stem Cell Biol 2019; 49 (1):e80 Isolation of Neural Stem Cells from Whole Brain Tissues of Adult Mice.

实验应用 : ICC/IF

种属反应 : Mouse

Peng YS et al. Cell Biol Toxicol 2019; (Epub) BSA-bounded p-cresyl sulfate potentiates the malignancy of bladder carcinoma by triggering cell migration and EMT through the ROS/Src/FAK signaling pathway.

实验应用 : WB

种属反应 : Human

Chu CA et al. EBioMedicine 2019; 43:270-281 MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway.

Chien CH et al. J Biomed Sci 2019; 26 (1):77 Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets.

实验应用 : WB

种属反应 : Human

Umeh-Garcia M et al. Cancer Res 2019; (Epub) A Novel Bioengineered MicroRNA-127 Prodrug Suppresses The Growth And Metastatic Potential Of Triple Negative Breast Cancer Cells.

实验应用 : IHC

种属反应 : Human

Kuo CY et al. Integr Cancer Ther 2019; 18:1534735419866924 Ethanol Extracts of Dietary Herb, Alpinia nantoensis, Exhibit Anticancer Potential in Human Breast Cancer Cells.

实验应用 : WB

种属反应 : Human

Chen KY et al. PLoS One 2019; 14 (7):e0219317 Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.

实验应用 : WB

种属反应 : Human

Shukla A et al. JCI Insight 2019; 5 Self-reactive B cells in the GALT are actively curtailed to prevent gut inflammation.

实验应用 : WB

种属反应 : Human

Su KJ et al. Cancers (Basel) 2019; 11 (8) Downregulation of SHIP2 by Hepatitis B Virus X Promotes the Metastasis and Chemoresistance of Hepatocellular Carcinoma through SKP2.

实验应用 : WB

种属反应 : Human

Hao S et al. J Cell Biochem 2019; 120 (9):15360-15368 MicroRNA-374c-5p inhibits the development of breast cancer through TATA-box binding protein associated factor 7-mediated transcriptional regulation of DEP domain containing 1.

实验应用 : WB

种属反应 : Human

Offer S et al. J Exp Clin Cancer Res 2019; 38 (1):241 Extracellular lipid loading augments hypoxic paracrine signaling and promotes glioma angiogenesis and macrophage infiltration.

实验应用 : WB

种属反应 : Human

Xie B et al. Mol Med Rep 2019; 20 (2):1808-1818 Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β?catenin pathway.

实验应用 : WB

种属反应 : Mouse

Chen HY et al. Antioxidants (Basel) 2019; 8 (4) Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo.

实验应用 : WB

种属反应 : Human

Diao P et al. J Cell Mol Med 2019; 23 (6):4269-4280 Overexpression of ZEB2-AS1 promotes epithelial-to-mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma.

实验应用 : WB

种属反应 : Human

Pei YF et al. Am J Pathol 2019; (Epub) Methyl-CpG Binding Domain Protein 2 Inhibits the Malignant Characteristic of Lung Adenocarcinoma through the Epigenetic Modulation of 10 to 11 Translocation 1 and miR-200s.

实验应用 : WB

种属反应 : Human

Ma C et al. Onco Targets Ther 2019; 12:1475-1495 Sympathetic innervation contributes to perineural invasion of salivary adenoid cystic carcinoma via the β2-adrenergic receptor.

实验应用 : WB

种属反应 : Human

Yu CY et al. Biochem Biophys Res Commun 2018; 506 (4):901-906 Transforming growth factor alpha promotes tumorigenesis and regulates epithelial-mesenchymal transition modulation in colon cancer.

实验应用 : WB

种属反应 : Human

Chang CY et al. Cell Death Discov 2018; 4:100 PEGylated liposome-encapsulated rhenium-188 radiopharmaceutical inhibits proliferation and epithelial-mesenchymal transition of human head and neck cancer cells in vivo with repeated therapy.

实验应用 : WB

种属反应 : Mouse

Chen HY et al. Cell Physiol Biochem 2018; 49 (5):1970-1986 Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression.

实验应用 : WB

种属反应 : Rat

Masaru Terasaki et al. J. Clin. Biochem. Nutr. 2018;:43107 Fucoxanthin administration delays occurrence of tumors in xenograft mice by colonospheres, with an anti-tumor predictor of glycine.

实验应用 : WB

种属反应 : Human

Nakazawa Y et al. Sci Rep 2018; 8 (1):4013 Periostin blockade overcomes chemoresistance via restricting the expansion of mesenchymal tumor subpopulations in breast cancer.

实验应用 : IHC-Fr

种属反应 : Human

Lin S et al. Nitric Oxide 2018; 76:16-28 Daily therapy with a slow-releasing H₂S donor GYY4137 enables early functional recovery and ameliorates renal injury associated with urinary obstruction.

实验应用 : WB

种属反应 : Rat

Magnani E et al. Biochim Biophys Acta 2018; (Epub) UHRF1 regulates CDH1 via promoter associated non-coding RNAs in prostate cancer cells.

实验应用 : WB

种属反应 : Human

Li CH et al. Arch Toxicol 2017; 91 (5):2165-2178 Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells.

Hua KT et al. Sci Rep 2017; 7 (1):4466 3'UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma.

实验应用 : WB

种属反应 : Human

Zheng X et al. Int J Oncol 2017; 50 (3):893-902 SB-T-121205, a next-generation taxane, enhances apoptosis and inhibits migration/invasion in MCF-7/PTX cells.

Pistore C et al. Oncogene 2017; (Epub) DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells.

实验应用 : WB

种属反应 : Human

Wang YY et al. Cancer Chemother Pharmacol 2017; 79 (6):1129-1140 CYT-Rx20 inhibits ovarian cancer cells in vitro and in vivo through oxidative stress-induced DNA damage and cell apoptosis.

实验应用 : WB

种属反应 : Human

Chiu JH et al. J Transl Med 2017; 15 (1):97 Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers.

实验应用 : WB

种属反应 : Human

Chen X et al. Tumour Biol 2017; 39 (3):1.01E+15 Sulfiredoxin may promote metastasis and invasion of cervical squamous cell carcinoma by epithelial-mesenchymal transition.

实验应用 : WB

种属反应 : Human

Tsai CH et al. Sci Rep 2017; 7:41927 The inhibition of lung cancer cell migration by AhR-regulated autophagy.

实验应用 : WB

种属反应 : Human

Lu CW et al. Cancer Lett 2017; 388:130-138 VLDL and LDL, but not HDL, promote breast cancer cell proliferation, metastasis and angiogenesis.

实验应用 : WB

Hsu CC et al. J Biomed Sci 2016; 23 (1):81 Suberoylanilide hydroxamic acid represses glioma stem-like cells.

Marquez-Vilendrer SB et al. Oncoscience 2016; 3 (43416):322-336 Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer development.

Hou YY et al. Oncol Lett 2016; 11 (6):4013-4021 Aberrant DNA hypomethylation of miR-196b contributes to migration and invasion of oral cancer.

实验应用 : WB

种属反应 : Human

Yin K et al. Oncotarget 2016; 7 (17):24537-48 MiR-206 suppresses epithelial mesenchymal transition by targeting TGF-β signaling in estrogen receptor positive breast cancer cells.

实验应用 : WB

种属反应 : Human

Li X et al. Am J Cancer Res 2016; 6 (12):2869-2879 MicroRNA-613 suppresses proliferation, migration and invasion of osteosarcoma by targeting c-MET.

实验应用 : WB

种属反应 : Human

Stefanie B. Marquez-Vilendrer et al. Oncoscience 2016; (Epub) Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer development.

实验应用 : IHC-P

种属反应 : Mouse

Ling HH et al. Exp Cell Res 2016; Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer.

实验应用 : WB

种属反应 : Human

Sridaran D et al. Tumour Biol 2016; Oxystressed tumor microenvironment potentiates epithelial to mesenchymal transition and alters cellular bioenergetics towards cancer progression.

实验应用 : WB

种属反应 : Human

Leyton-Puig D et al. Biol Open 2016; 5 (7):1001-9 PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins.

Li SW et al. Sci Rep 2016; 6:25754 SARS coronavirus papain-like protease induces Egr-1-dependent up-regulation of TGF-β1 via ROS/p38 MAPK/STAT3 pathway.

实验应用 : WB, ICC/IF

种属反应 : Human

Hung AC et al. Clin Cancer Res 2016; (Epub) Extracellular Visfatin-Promoted Malignant Behavior in Breast Cancer Is Mediated Through c-Abl and STAT3 Activation.

实验应用 : IHC-P

种属反应 : Human

Pon JR et al. Nat Commun 2015; 6:7953 MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation.

实验应用 : WB

种属反应 : Human

Wang TH et al. Oncotarget 2015; 6 (27):23342-57 Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition.

实验应用 : WB, IHC-P

种属反应 : Human

Yeh SI et al. Invest Ophthalmol Vis Sci 2015; 56 (4):2126-34 Pigment Epithelial-Derived Factor Peptide Facilitates the Regeneration of a Functional Limbus in Rabbit Partial Limbal Deficiency.

实验应用 : IHC-P

Succoio M et al. J Proteomics 2015; 128 (Epub):18-29 Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescence.

实验应用 : WB

种属反应 : Human

Huang RF et al. Int J Nanomedicine 2015; 10:2823-46 Inhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene.

实验应用 : WB

种属反应 : Human

Wai-Theng Lee et al. Food and Chemical Toxicology 2015; 78:33-41 Antroquinonol from Antrodia Camphorata suppresses breast tumor migration/invasion through inhibiting ERK-AP-1- and AKT-NF-κBdependent MMP-9 and epithelial-mesenchymal transition expressions

实验应用 : WB

种属反应 : Human

Szu-Ting Lin et al. Cellular and Molecular Life Sciences 2015; 72 (12):2395-409 pgrmc1 contributes to *-induced chemoresistance in mes-sa uterine sarcoma.

实验应用 : WB

种属反应 : Human

Wei HJ et al. Oncotarget 2014; 5 (19):9514-29 FOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cells.

Otti GR et al. PLoS One 2014; 9 (11):e112723 notch2 controls prolactin and *-like growth factor binding protein-1 expression in decidualizing human stromal cells of early pregnancy.

实验应用 : ICC/IF

种属反应 : Human

Lei M et al. Biomaterials 2014; 35 (24):6332-43 Mesenchymal stem cell characteristics of dental pulp and periodontal ligament stem cells after in-vivo transplantation.

实验应用 : ICC/IF

种属反应 : Human

Barrette K et al. Br J Dermatol 2014; Epithelial-Mesenchymal Transition during invasion of cutaneous Squamous Cell Carcinoma is paralleled by AKT activation.

实验应用 : WB

种属反应 : Human

Haider S et al. Endocrinology 2014; 155 (1):263-74 Notch signaling plays a critical role in motility and differentiation of human first-trimester cytotrophoblasts.

Wang S et al. J Biol Chem 2013; 288 (36):26265-74 Progesterone receptor A stability is mediated by glycogen synthase kinase-3β in the Brca1-deficient mammary gland.

实验应用 : WB

种属反应 : Human

Chen JY et al. J Biomed Sci 2013; 20:95 quercetin-induced cardioprotection against * cytotoxicity.

实验应用 : WB

种属反应 : Rat

Smith A et al. Biotech Histochem 2013; Finding the best antibody dilution by repeated immunostaining of the same tissue section.

实验应用 : IHC-P

Chen JY et al. J Nutr Biochem 2013; 24 (11):1889-910 High glucose-induced proteome alterations in hepatocytes and its possible relevance to diabetic liver disease.

实验应用 : WB

种属反应 : Human

Lin ST et al. J Pharm Biomed Anal 2013; 78-79:43108 redox-proteomic analysis of * resistance-induced altered thiol activity in uterine carcinoma.

实验应用 : WB

种属反应 : Human

Vannier C et al. J Biol Chem 2013; 288 (38):27619-37 The Bin/amphiphysin/Rvs (BAR) domain protein endophilin B2 interacts with plectin and controls perinuclear cytoskeletal architecture.

实验应用 : ICC/IF

种属反应 : Human

Hsu HY et al. Evid Based Complement Alternat Med 2012; 2012:819632 Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells.

实验应用 : WB

种属反应 : Human

Julia Pon et al. 0 2010; THE MEF2B REGULATORY NETWORK.

实验应用 : WB

种属反应 : Human

Cho CK et al. J Proteome Res 2010; 9 (7):3574-82 Amniotic fluid proteome analysis from Down syndrome pregnancies for biomarker discovery.

实验应用 : WB

种属反应 : Human

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