应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500-1:3000 |
| 1:100-1:1000 |
| 1:100-1:1000 |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
阳性对照
IMR32 , U87-MG
预测种属反应
Rat, Bovine, Chimpanzee(>80% identity)
形式
Liquid
存储溶液
PBS, 1% BSA, 20% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant protein encompassing a sequence within the center region of human XPD. The exact sequence is proprietary.
纯化方式
Purified by antigen-affinity chromatography.
偶联
Unconjugated
RRID
AB_10616680
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
ERCC excision repair 2, TFIIH core complex helicase subunit , COFS2 , EM9 , TFIIH , TTD , TTD1 , XPD
细胞定位
Nucleus
功能与背景
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
数据库
研究领域
![Anti-XPD antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX105357](/upload/website/prouct_img/small/GTX105357/GTX105357_40275_IHC_M_w_23060120_709.webp "Anti-XPD antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX105357")
![Anti-XPD antibody [N2C2], Internal used in Western Blot (WB). GTX105357](/upload/website/prouct_img/small/GTX105357/GTX105357_WB_w_23060120_846.webp "Anti-XPD antibody [N2C2], Internal used in Western Blot (WB). GTX105357")
![Anti-XPD antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX105357](/upload/website/prouct_img/small/GTX105357/GTX105357_40275_IHC_w_23060120_421.webp "Anti-XPD antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX105357")
![Anti-XPD antibody [N2C2], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX105357](/upload/website/prouct_img/small/GTX105357/GTX105357_40275_20180809_ICC_IF_UVC_w_23060120_181.webp "Anti-XPD antibody [N2C2], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX105357")
![Anti-XPD antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX105357](/upload/website/prouct_img/normal/GTX105357/GTX105357_40275_IHC_M_w_23060120_709.webp "Anti-XPD antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX105357")
![Anti-XPD antibody [N2C2], Internal used in Western Blot (WB). GTX105357](/upload/website/prouct_img/normal/GTX105357/GTX105357_WB_w_23060120_846.webp "Anti-XPD antibody [N2C2], Internal used in Western Blot (WB). GTX105357")
![Anti-XPD antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX105357](/upload/website/prouct_img/normal/GTX105357/GTX105357_40275_IHC_w_23060120_421.webp "Anti-XPD antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX105357")
![Anti-XPD antibody [N2C2], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX105357](/upload/website/prouct_img/normal/GTX105357/GTX105357_40275_20180809_ICC_IF_UVC_w_23060120_181.webp "Anti-XPD antibody [N2C2], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX105357")
