beta Catenin抗体 [N1N2-2], N-term

Name: beta Catenin抗体 [N1N2-2], N-term
Brand: GeneTex
SKU: GTX101435
Price: 4000.00 RMB
Rating: 4.3 (7 reviews)

Anti-beta Catenin antibody [N1N2-2], N-term used in IHC (Paraffin sections) (IHC-P). GTX101435

Anti-beta Catenin antibody [N1N2-2], N-term used in Western Blot (WB). GTX101435

Anti-beta Catenin antibody [N1N2-2], N-term used in ChIP assay (ChIP assay). GTX101435

Anti-beta Catenin antibody [N1N2-2], N-term used in Immunoprecipitation (IP). GTX101435

Anti-beta Catenin antibody [N1N2-2], N-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX101435

Anti-beta Catenin antibody [N1N2-2], N-term used in Flow cytometry (FACS). GTX101435

Anti-beta Catenin antibody [N1N2-2], N-term used in IHC (Whole mount) (IHC-Wm). GTX101435

Anti-beta Catenin antibody [N1N2-2], N-term used in Immunohistochemistry (IHC). GTX101435

Anti-beta Catenin antibody [N1N2-2], N-term used in Western Blot and Immunoprecipitation (WB IP). GTX101435

目录号 GTX101435

文献引用 54

宿主	Rabbit
克隆	Polyclonal
同种型	IgG
实验应用	WB, ICC/IF, IHC-P, IHC-Fr, IHC-Wm, FACS, IP, ChIP assay, IHC
种属反应	Human, Mouse, Rat, Zebrafish, Rabbit, Cat, Dog
产品包装	100 μl (¥4000), 25 μl (¥1700)

查看所有 beta Catenin 的产品

View product citations for antibody GTX101435 on CiteAb

产品说明

摘要

Beta-catenin antibody recognizes beta-catenin protein, which acts as a cell adhesion factor as well as an effector of Wnt signaling pathway-driven transcription. Mutation or dysregulation of beta-catenin is associated with many diseases, including developmental disorders and cancers. There are a plethora of commercially available beta-catenin antibodies, among which GeneTex’s beta-catenin antibody (GTX101435) is one of the most rigorously validated and widely cited for a number of applications.

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认

实验应用	稀释倍数
WB	1:500-1:20000
ICC/IF	1:100-1:1000
IHC-P	1:100-1:1000
IHC-Fr	Assay dependent
IHC-Wm	Assay dependent
FACS	1:50-1:200
IP	1:50-1:100
ChIP assay	Assay dependent
IHC	Assay dependent

WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

85 kDa. ( Note )

阳性对照

Mouse brain , PC-12 , HeLa

预测种属反应

Sheep, Bovine, Chicken, Pig, Xenopus tropicalis, Rhesus Monkey(>80% identity)

产品属性

形式

Liquid

存储溶液

PBS, 1% BSA, 20% Glycerol

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

0.07 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Recombinant protein encompassing a sequence within the N-terminus region of human beta Catenin. The exact sequence is proprietary.

纯化方式

Purified by antigen-affinity chromatography.

偶联

Unconjugated

RRID

AB_1950062

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

别名

catenin beta 1 , CTNNB , EVR7 , MRD19 , armadillo

细胞定位

Cytoplasm , Nucleus , cytoskeleton

功能与背景

Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM]

数据库

Gene ID: 1499 CTNNB1
UniProt: P35222 CTNNB1

研究领域

產品图片

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2] detects beta Catenin protein at cell membrane in mouse colon by immunohistochemical analysis.
Sample: Paraffin-embedded mouse colon.
Green: beta Catenin antibody [N1N2-2] (GTX101435) diluted at 1:500.
Red: alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:500.
Blue: Hoechst 33342 staining.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 WB Image

Wild-type (WT) and beta Catenin knockout (KO) 293T cell extracts (9 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX101435 IHC-P Image

GTX101435 WB Image

Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membranes were blotted with beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:1000 and competitor's antibody diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

*The competitor is not affiliated with GeneTex and does not endorse this product.

GTX101435 IHC-P Image

Immunohistochemical analysis of paraffin-embedded zebrafish tissue, using beta Catenin antibody [N1N2-2], N-term (GTX101435) at 1:300 dilution.

GTX101435 WB Image

Non-transfected (–) and transfected (+) HeLa whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at cell membrane and cytoplasm in rat duodenum by immunohistochemical analysis.
Sample: Paraffin-embedded rat duodenum.
beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 WB Image

Sample (50 μg of whole cell lysate)
A: mouse brain
7.5% SDS PAGE
GTX101435 diluted at 1:1000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX101435 ChIP assay Image

Cross-linked ChIP was performed with HCT116 chromatin extract and 5 μg of either control rabbit IgG or anti-beta Catenin antibody. The precipitated DNA was detected by PCR with primer set targeting to c-Myc promoter.

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at cell membrane and cytoplasm in mouse duodenum by immunohistochemical analysis.
Sample: Paraffin-embedded mouse duodenum.
beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 IP Image

Immunoprecipitation of beta Catenin protein from HeLa whole cell extracts using 5 μg of beta Catenin antibody (GTX101435).
Western blot analysis was performed using beta Catenin antibody (GTX101435).
EasyBlot anti-Rabbit IgG (GTX221666-01) was used as a secondary reagent.

GTX101435 ICC/IF Image

Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed A431, using beta Catenin(GTX101435) antibody (Green) at 1:200 dilution. Alpha-tubulin filaments were labeled with GTX11304 (Red) at 1:2000.

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at cell membrane and cytoplasm in human esophagus by immunohistochemical analysis.
Sample: Paraffin-embedded human esophagus.
beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at membrane on mouse skin by immunohistochemical analysis.
Sample: Paraffin-embedded mouse skin.
beta Catenin antibody [N1N2-2], N-term (GTX101435) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at membrane on mouse colon by immunohistochemical analysis.
Sample: Paraffin-embedded mouse colon.
beta Catenin antibody [N1N2-2], N-term (GTX101435) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX101435 FACS Image

beta Catenin antibody [N1N2-2], N-term (GTX101435) detects CTNNB1 protein by flow cytometry analysis.
Sample: HeLa cell.
Black: Unlabelled sample was used as a control.
Red: beta Catenin antibody [N1N2-2], N-term (GTX101435) dilution: 1:50.
Acquisition of 20,000 events were collected for FACS analysis.

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at cell membrane and cytoplasm in rat colon by immunohistochemical analysis.
Sample: Paraffin-embedded rat colon.
beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:10000.

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at cell membrane and cytoplasm in human cervix by immunohistochemical analysis.
Sample: Paraffin-embedded human cervix.
beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 IHC-P Image

GTX101435 WB Image

beta Catenin antibody [N1N2-2], N-term detects CTNNB1 protein by western blot analysis.
A. 30 μg PC-12 whole cell lysate/extract |
7.5% SDS-PAGE
beta Catenin antibody [N1N2-2], N-term (GTX101435) dilution: 1:1000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX101435 ICC/IF Image

beta Catenin antibody detects beta Catenin protein at cell membrane by immunofluorescent analysis.
Sample: MDCK cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: beta Catenin stained by beta Catenin antibody (GTX101435) diluted at 1:1000.

GTX101435 IHC-P Image

beta Catenin antibody detects beta Catenin protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded cat colon.
beta Catenin stained by beta Catenin antibody (GTX101435) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 IHC-Wm Image

beta Catenin antibody [N1N2-2], N-term detects Ctnnb1 protein on zebrafish by whole mount immunohistochemical analysis.
Sample: 2 days-post-fertilization zebrafish embryo.
beta Catenin antibody [N1N2-2], N-term (GTX101435) dilution: 1:100.

GTX101435 IHC-Wm Image

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein by immunohistochemical analysis.
Sample: Paraffin-embedded rat tissues.
beta Catenin stained by beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein by immunohistochemical analysis.
Sample: Paraffin-embedded mouse tissues.
beta Catenin stained by beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 WB Image

Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with beta Catenin antibody (GTX101435) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

GTX101435 IHC-P Image

beta Catenin antibody detects beta Catenin protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded cat liver.
beta Catenin stained by beta Catenin antibody (GTX101435) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 IHC-Wm Image

beta Catenin antibody [N1N2-2], N-term detects Ctnnb1 protein on zebrafish by whole mount immunohistochemical analysis.
Sample: 1 day-post-fertilization zebrafish embryo.
beta Catenin antibody [N1N2-2], N-term (GTX101435) dilution: 1:100.

GTX101435 IHC Image

Immunohistochemical analysis of agarose-embedded zebrafish embryo, using beta Catenin antibody [N1N2-2], N-term GTX101435) at 1:100. dilution. (This image was provided courtesy of the Schilling Lab at UC, Irvine.)

GTX101435 WB Image

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at cell membrane and cytoplasm in mouse intestine by immunohistochemical analysis.
Sample: Paraffin-embedded mouse intestine.
beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX101435 ICC/IF Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at cell membrane by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: beta Catenin protein stained by beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.
Blue: Hoechst 33342 staining.

GTX101435 IHC-P Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at membrane on mouse urinary bladder by immunohistochemical analysis.
Sample: Paraffin-embedded mouse urinary bladder.
beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX101435 ICC/IF Image

beta Catenin antibody [N1N2-2], N-term detects beta Catenin protein at cell membrane by immunofluorescent analysis.
Sample: HCT 116 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: beta Catenin protein stained by beta Catenin antibody [N1N2-2], N-term (GTX101435) diluted at 1:500.
Blue: Hoechst 33342 staining.

GTX101435 WB Image

Various tissue extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with beta Catenin antibody (GTX101435) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX101435 WB Image

The data was published in the journal Evid Based Complement Alternat Med in 2012.PMID: 23320038

GTX101435 WB IP Image

The data was published in the journal Cell Adh Migr in 2019. PMID: 30744493

GTX101435 WB Image

The data was published in the journal Oncotarget in 2018. PMID: 30613366

文献引用

Application Reference

Gao W et al. BMC Cardiovasc Disord 2024; 24 (1) : 82 Mycn ameliorates cardiac hypertrophy-induced heart failure in mice by mediating the USP2/JUP/Akt/β-catenin cascade.

J Huang et al. Cell Death Dis 2024; 15 (2) : 139 SALL4 promotes cancer stem-like cell phenotype and radioresistance in oral squamous cell carcinomas via methyltransferase-like 3-mediated m6A modification

实验应用 : IHC-P

Kajihara R et al. Poult Sci 2023; 103 (2) : 103361 Wnt signaling blockade is essential for maintaining the pluripotency of chicken embryonic stem cells.

R Kajihara et al. Poult Sci 2023; Wnt signaling blockade is essential for maintaining the pluripotency of chicken embryonic stem cells

实验应用 : WB

? ?en et al. ACS Appl Mater Interfaces 2023; 15 (50) : 58260-58273 Microglia Polarization and Antiglioma Effects Fostered by Dual Cell Membrane-Coated Doxorubicin-Loaded Hexagonal Boron Nitride Nanoflakes

显示更多 +

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产品评论

beta Catenin antibody [N1N2-2], N-term 目录号 GTX101435

Rating

( Average 4.3 based on 7 users reviews)

实验应用

Western Blot(WB)		( Average 4.2 based on 5 users reviews)
Immunocytochemistry/ Immunofluorescence(ICC/IF)		( Average 4 based on 1 users reviews)
IHC (Paraffin sections)(IHC-P)		( Average 5 based on 1 users reviews)

Date : Hu Jing-Lan submitted on 30-May-2021

Score :

Application Tested : ICC/IF

Sample Species : Hu

Sample : MCF7 cells

Blocking : 1% BSA in PBST, 37°C, 1Hr

Fixation : 4% PFA

Permeabilization /Antigen retrieval : 0.1% Triton

Primary Antibody : 1:500, 4°C, 16Hr

Date : Anonymous submitted on 13-May-2021

Score :

Application Tested : IHC-P

Sample Species : Ms

Sample : Intestine tumor

Fixation : 4% PFA in PBS

Permeabilization /Antigen retrieval : Citrate buffer pH6, boil°C, 0.5Hr

Primary Antibody : 1:100, 4°C, 16Hr

Date : Anonymous submitted on 13-May-2021

Score :

Application Tested : WB

Sample Species : Ms

Sample : Intestinal tissue lysates

Amount used : 20 μg

Blocking : 5 % milk in PBS, RT°C, 1Hr

Primary Antibody : 1:1000, 4°C, 16Hr

Date : Anonymous submitted on 01-Oct-2019

Score :

Application Tested : WB

Sample Species : Hu

Sample : Huh7 cells

Amount used : 5 μg

Blocking : 2.5% non-fat milk, 25°C, 0.5Hr

Primary Antibody : 1:2000, 25°C, 4Hr

Date : Anonymous submitted on 17-Jun-2016

Score :

Application Tested : WB

Sample Species : Hu

Sample : 293T cells

Amount used : 60μg

Blocking : 5% milk, 24°C, 1.5Hr

Primary Antibody : 1:1200, 4°C, 16Hr

条带说明 : Lane 1: 293T cells, Lane 2-3: knockdown of β Catenin in 293T cells

Date : Anonymous submitted on 28-May-2015

Score :

Application Tested : WB

Sample Species : Hu

Sample : LX2 cells

Amount used : 10μg

Blocking : 5% skim milk in TBST, 25°C, 1Hr

Primary Antibody : 1:500, 4°C, 16Hr

条带说明 : Lane 1: LX2 cells.Lane 2: LX2 cells (TGF-beta treatment).

Date : Anonymous submitted on 31-Mar-2015

Score :

Application Tested : WB

Sample Species : Hu

Sample : fibroblast cells

Amount used : 30μg

Blocking : 5% milk in TBST, 25°C, 1Hr

Primary Antibody : 1:2000, 4°C, 16Hr

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我要评论产品

Application Reference

Gao W et al. BMC Cardiovasc Disord 2024; 24 (1):82 Mycn ameliorates cardiac hypertrophy-induced heart failure in mice by mediating the USP2/JUP/Akt/β-catenin cascade.

J Huang et al. Cell Death Dis 2024; 15 (2):139 SALL4 promotes cancer stem-like cell phenotype and radioresistance in oral squamous cell carcinomas via methyltransferase-like 3-mediated m6A modification

实验应用 : IHC-P

Kajihara R et al. Poult Sci 2023; 103 (2):103361 Wnt signaling blockade is essential for maintaining the pluripotency of chicken embryonic stem cells.

R Kajihara et al. Poult Sci 2023; Wnt signaling blockade is essential for maintaining the pluripotency of chicken embryonic stem cells

实验应用 : WB

? ?en et al. ACS Appl Mater Interfaces 2023; 15 (50):58260-58273 Microglia Polarization and Antiglioma Effects Fostered by Dual Cell Membrane-Coated Doxorubicin-Loaded Hexagonal Boron Nitride Nanoflakes

Jianhua We et al. Research Square 2023; SALL4 promotes cancer stem-like cell phenotype and radioresistance in oral squamous cell carcinomas via methyltransferase-like 3-mediated m6A modification

实验应用 : IHC-P

Sun L et al. Front Cell Infect Microbiol 2023; 13:1126516 Neutrophil extracellular traps promote bronchopulmonary dysplasia-like injury in neonatal mice via the WNT/β-catenin pathway.

Hsu YC et al. Int J Mol Sci 2023; 24 (8) Dickkopf-1 Acts as a Profibrotic Mediator in Progressive Chronic Kidney Disease.

Wang X et al. Heliyon 2023; 9 (4):e14800 Fabrication of bFGF/polydopamine-loaded PEEK implants for improving soft tissue integration by upregulating Wnt/β-catenin signaling.

实验应用 : WB

种属反应 : Rabbit

Li H et al. Toxicol Res (Camb) 2022; 11 (3):437-450 Dimethyl fumarate ameliorates lipopolysaccharide-induced acute lung injury by inhibiting NLRP3 inflammasome-mediated pyroptosis through enhancing Nrf2 signaling.

Shiba F et al. Int J Dent 2022; 2022:7398924 Equisetum arvense Inhibits Alveolar Bone Destruction in a Rat Model with Lipopolysaccharide (LPS)-Induced Periodontitis.

Su MT et al. Pharmaceuticals (Basel) 2022; 15 (12) Aspirin Inhibits Fibronectin Expression and Reverses Fibronectin-Mediated Cell Invasiveness by Activating Akt Signaling in Preeclampsia.

Martin JB et al. Front Cell Dev Biol 2022; 10:840129 Arvcf Dependent Adherens Junction Stability is Required to Prevent Age-Related Cortical Cataracts.

实验应用 : IHC-Fr

种属反应 : Mouse

Evdokia Bogdanova et al. Int J Mol Sci 2021; 22 (9) Myocardial Hypertrophy and Fibrosis Are Associated with Cardiomyocyte Beta-Catenin and TRPC6/Calcineurin/NFAT Signaling in Spontaneously Hypertensive Rats with 5/6 Nephrectomy.

实验应用 : IHC-P

种属反应 : Rat

Chi-Cheng Lu et al. Exp Ther Med 2021; 22 (2):822 Dracorhodin perchlorate enhances wound healing via β-catenin, ERK/p38, and AKT signaling in human HaCaT keratinocytes.

实验应用 : WB

种属反应 : Human

Hsuan-Fu Kuo et al. Biomedicines 2021; 9 (10) Endocardial Endothelial Dysfunction and Unknown Polymorphic Composite Accumulation in Heart Failure.

种属反应 : Human, Rat

Park M et al. Int J Mol Sci 2021; 22 (22) Human Pluripotent Stem Cell-Derived Neural Progenitor Cells Promote Retinal Ganglion Cell Survival and Axon Recovery in an Optic Nerve Compression Animal Model.

实验应用 : WB

种属反应 : Human

Morita A et al. Biochem Biophys Rep 2021; 28:101181 Glycyrrhizin and its derivatives promote hepatic differentiation via sweet receptor, Wnt, and Notch signaling.

实验应用 : FACS

种属反应 : Human

Chen YL et al. Am J Cancer Res 2021; 11 (9):4277-4293 Serine/threonine-protein kinase 24 is an inhibitor of gastric cancer metastasis through suppressing CDH1 gene and enhancing stemness.

实验应用 : WB

种属反应 : Human

Chan YJ et al. Part Fibre Toxicol 2021; 18 (1):4 Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation.

实验应用 : WB

种属反应 : Human

Yin L et al. Aging (Albany NY) 2020; 12 (9):8261-8288 Identification of candidate lncRNAs and circRNAs regulating WNT3/β-catenin signaling in essential hypertension.

Chang YX et al. Cancers (Basel) 2020; 12 (12) Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3β-β-Catenin and XIAP-Survivin Pathways.

实验应用 : WB

种属反应 : Human

Wang H et al. Br J Haematol 2020; 189 (6):1151-1164 Lycorine Targets Multiple Myeloma Stem Cell-Like Cells by Inhibition of Wnt/β-catenin Pathway.

实验应用 : WB

种属反应 : Human

Fang CH et al. J Biomed Sci 2020; 27 (1):42 A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and 帣-catenin-ABCG2 signaling.

实验应用 : WB

种属反应 : Human

M?nica G Mendoza-Rodr?guez et al. Int J Mol Sci 2020; 21 (6) Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated Tumorigenesis.

实验应用 : IHC-P

种属反应 : Mouse

Jiang X et al. J Stomatol Oral Maxillofac Surg 2020; (Epub) Bone regeneration and mineralisation was promoted during distraction osteogenesis by human periostin gene in rabbit mandibular model.

实验应用 : WB

种属反应 : Rabbit

Raineri A et al. Int J Mol Sci 2019; 20 (23) Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability.

Tsai CH et al. Biochim Biophys Acta Mol Cell Res 2019; 1867 (2):118564 Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKC帢-mediated AHR-HDAC interactions.

实验应用 : WB

种属反应 : Human

Callejas BE et al. Int J Cancer 2019; (Epub) Helminth-derived molecules inhibit colitis-associated colon cancer development through NF-庥B and STAT3 regulation.

实验应用 : IHC-P

种属反应 : Mouse

Shen HH et al. J Biomed Sci 2019; 26 (1):62 Raloxifene inhibits adipose tissue inflammation and adipogenesis through Wnt regulation in ovariectomized rats and 3?3-L1 cells.

实验应用 : WB

种属反应 : Rat

Fang Y et al. Nat Commun 2019; 10 (1):3981 CD36 inhibits 帣-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis.

实验应用 : IHC-P

种属反应 : Human

Lin JH et al. Cell Adh Migr 2019;:1-18 Small G protein signalling modulator 2 (SGSM2) is involved in oestrogen receptor-positive breast cancer metastasis through enhancement of migratory cell adhesion via interaction with E-cadherin.

实验应用 : WB

种属反应 : Human

Jakubzig B et al. Cancers (Basel) 2018; 10 (12) Mechanisms of Matrix-Induced Chemoresistance of Breast Cancer Cells-Deciphering Novel Potential Targets for a Cell Sensitization.

实验应用 : WB, FACS

Fang F et al. Oncotarget 2018; 9 (95):36780-36792 Targeting the Wnt/β-catenin pathway in human osteosarcoma cells.

实验应用 : WB

种属反应 : Human

Leon-Cabrera S et al. Cancers (Basel) 2018; 10 (9) Deficiency in STAT1 Signaling Predisposes Gut Inflammation and Prompts Colorectal Cancer Development.

实验应用 : IHC-P

种属反应 : Mouse

Yan W et al. J Cell Physiol 2018; (Epub) Suppression of SEMA6C promotes preantral follicles atresia with decreased cell junctions in mice ovaries.

实验应用 : WB

种属反应 : Mouse

Chen Z et al. Cancer Lett 2018; (Epub) LncTIC1 interacts with β-catenin to drive liver TIC self-renewal and liver tumorigenesis.

实验应用 : WB

种属反应 : Human

Ogawa T et al. Oncotarget 2017; 8 (68):112550-112564 ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway.

Piva MBR et al. Cancers (Basel) 2017; 9 (9) integrin activation contributes to lower * sensitivity in mv3 melanoma cells by inducing the wnt signalling pathway.

实验应用 : FACS

种属反应 : Human

Yen CH et al. Journal of Ethnopharmacology 2017; (Epub) gynura divaricata attenuates tumor growth and tumor relapse after * therapy in hcc xenograft model through suppression of cancer stem cell growth and wnt.

Lin HC et al. J Agric Food Chem 2017; 65 (1):51-59 Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets.

实验应用 : WB

种属反应 : Human

Lu J et al. EMBO Rep 2017; (Epub) The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice.

实验应用 : WB, IP

种属反应 : Mouse

Kung YA et al. Nucleic Acids Res 2016; Control of the negative IRES trans-acting factor KHSRP by ubiquitination.

实验应用 : WB

种属反应 : Human

Li CH et al. Arch Toxicol 2016; (Epub) Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells.

实验应用 : WB

种属反应 : Human

Lee JG et al. J Biol Chem 2015; 290 (44):26752-64 WNT10B enhances proliferation through β-catenin and RAC1 GTPase in human corneal endothelial cells.

实验应用 : WB

种属反应 : Human

Thiyagarajan V et al. PLoS One 2015; 10 (10):e0141285 Antroquinonol Targets FAK-Signaling Pathway Suppressed Cell Migration, Invasion, and Tumor Growth of C6 Glioma.

实验应用 : WB

种属反应 : Rat

Chiang CY et al. Clin Cancer Res 2015; 21 (24):1352069 SH3BGRL3 Protein as a Potential Prognostic Biomarker for Urothelial Carcinoma: A Novel Binding Partner of Epidermal Growth Factor Receptor.

实验应用 : WB

种属反应 : Human

Huang RF et al. Int J Nanomedicine 2015; 10:2823-46 Inhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene.

实验应用 : WB

种属反应 : Human

Nakagawa H et al. Proc Natl Acad Sci U S A 2014; 111 (3):1090-5 Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.

实验应用 : WB

种属反应 : Human

Turato C et al. Br J Cancer 2014; 110 (11):2708-15 SERPINB3 is associated with TGF-β1 and cytoplasmic β-catenin expression in hepatocellular carcinomas with poor prognosis.

实验应用 : IHC-P

种属反应 : Human

Hsu TH et al. Cell Death Differ 2014; Involvement of RARRES3 in the regulation of Wnt proteins acylation and signaling activities in human breast cancer cells.

实验应用 : WB

种属反应 : Human

Lee JG et al. Mol Cell Biol 2014; IL-1β-induced Wnt5a enhances human corneal endothelial cell migration through regulation of Cdc42 and RhoA.

实验应用 : WB

种属反应 : Human

Tsai TH et al. PLoS One 2014; 9 (4):e95443 Pigment Epithelium-Derived Factor 34-mer Peptide Prevents Liver Fibrosis and Hepatic Stellate Cell Activation through Down-Regulation of the PDGF Receptor.

实验应用 : WB

种属反应 : Rat

Hsu HY et al. Evid Based Complement Alternat Med 2012; 2012:819632 Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells.

实验应用 : WB

种属反应 : Human

SDS
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Glycerol.pdf
Proclin.pdf

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