形式
Liquid
存储溶液
10mM Sodium HEPES pH7.5, 150mM Sodium Chloride, 0.1mg/ml BSA, 50% Glycerol
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
免疫原种属
Human
免疫原
Synthetic peptide corresponding to residues surrounding Tyr1234 of human Met.
纯化方式
Unpurified
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
AUTS9 , DFNB97 , HGFR , MET , MET protooncogene, receptor tyrosine kinase , RCCP2 , cMet , hepatocyte growth factor receptor , C-Met , MET proto-oncogene, receptor tyrosine kinase
细胞定位
Membrane,Secreted
功能与背景
This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]
数据库
研究领域
![Anti-c-Met antibody [3i20(25H2)] used in Western Blot (WB). GTX14700](/upload/website/prouct_img/small/GTX14700/GTX14700_20191203_WB_46_w_23060620_293.webp "Anti-c-Met antibody [3i20(25H2)] used in Western Blot (WB). GTX14700")
![Anti-c-Met antibody [3i20(25H2)] used in Western Blot (WB). GTX14700](/upload/website/prouct_img/normal/GTX14700/GTX14700_20191203_WB_46_w_23060620_293.webp "Anti-c-Met antibody [3i20(25H2)] used in Western Blot (WB). GTX14700")
