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p53抗体

Anti-p53 antibody used in Western Blot (WB). GTX50438
Anti-p53 antibody used in IHC (Paraffin sections) (IHC-P). GTX50438
Anti-p53 antibody used in IHC (Paraffin sections) (IHC-P). GTX50438
Anti-p53 antibody used in Western Blot (WB). GTX50438
Anti-p53 antibody used in IHC (Paraffin sections) (IHC-P). GTX50438
Anti-p53 antibody used in IHC (Paraffin sections) (IHC-P). GTX50438
Anti-p53 antibody used in Immunoprecipitation (IP). GTX50438
Anti-p53 antibody used in Western Blot (WB). GTX50438
Anti-p53 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50438

目录号 GTX50438

文献引用 2

宿主

 Rabbit

克隆

 Polyclonal

同种型

 IgG

实验应用

 WB, ICC/IF, IHC-P, IP

种属反应

 Human, Mouse, Rat
产品包装
100 μl (¥5300)
查看所有 p53 的产品

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB 1:500-1:1000
ICC/IF 1:100-1:200
IHC-P 1:50-1:100
IP Assay dependent
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

44 kDa. ( Note )

产品属性

形式

Liquid

存储溶液

PBS, 150mM NaCl, 50% Glycerol

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

1 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

免疫原

Peptide sequence around aa.13~17 (P-L-S-Q-E) derived from human p53.

纯化方式

Purified by antigen-affinity chromatography.

偶联

Unconjugated

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

tumor protein p53 , BCC7 , BMFS5 , LFS1 , P53 , TRP53

细胞定位

Cytoplasm,Nucleus,Endoplasmic reticulum,Mitochondrion matrix

功能与背景

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

数据库

研究领域

產品图片

Anti-p53 antibody used in Western Blot (WB). GTX50438

GTX50438 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with p53 antibody (GTX50438) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-p53 antibody used in IHC (Paraffin sections) (IHC-P). GTX50438

GTX50438 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX50438 p53 antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

Anti-p53 antibody used in IHC (Paraffin sections) (IHC-P). GTX50438

GTX50438 IHC-P Image

IHC-P analysis of rat breast tissue sections using GTX50438 p53 antibody.

Anti-p53 antibody used in Western Blot (WB). GTX50438

GTX50438 WB Image

WB analysis of extracts from various sample using GTX50438 p53 antibody.
Lane 1 : rat breast tissue
Lane 2 : rat colon tissue
Dilution : 1:1000

Anti-p53 antibody used in IHC (Paraffin sections) (IHC-P). GTX50438

GTX50438 IHC-P Image

IHC-P analysis of rat breast tissue using GTX50438 p53 antibody.
Dilution : 1:100

Anti-p53 antibody used in IHC (Paraffin sections) (IHC-P). GTX50438

GTX50438 IHC-P Image

IHC-P analysis of rat colon tissue sections using GTX50438 p53 antibody.

Anti-p53 antibody used in Immunoprecipitation (IP). GTX50438

GTX50438 IP Image

IP analysis of extracts from 293T cells using GTX50438 p53 antibody.

Anti-p53 antibody used in Western Blot (WB). GTX50438

GTX50438 WB Image

WB analysis of extracts from mouse brain tissue using GTX50438 p53 antibody.

Anti-p53 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50438

GTX50438 ICC/IF Image

ICC/IF analysis of methanol-fixed HeLa cells using GTX50438 p53 antibody.

文献引用

Application Reference

Rashno Z et al. Sci Rep 2023; 13 (1) : 11465 Design of ion channel blocking, toxin-like Kunitz inhibitor peptides from the tapeworm, Echinococcus granulosus, with potential anti-cancer activity.
Trujillo-Uscanga A et al. Virology 2020; 550 : 78-88 Host cell p53 associates with the feline calicivirus major viral capsid protein VP1, the protease-polymerase NS6/7, and the double-stranded RNA playing a role in virus replication.
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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
产品包装 报价 (¥)
¥ 5300
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