产品说明
摘要
Pan-Cytokeratin antibody [PCK-26] is a mouse monoclonal antibody that detects multiple cytokeratins (i.e., Type II cytokeratins 1, 5, 6, and 8), a group of intermediate filament proteins present in most human epithelial tissues. This reagent is a broad spectrum antibody that reacts with a variety of normal, reactive, and neoplastic epithelial tissues, as well as simple, cornifying, and non-cornifying squamous epithelia and pseudostratified epithelia.
产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| Assay dependent |
| Assay dependent |
| 1:300 |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
产品说明
The antibody recognizes an epitope located on the Type II cytokeratins 1, 5, 6, and 8. PCK-26 is a broad spectrum antibody which reacts specifically with a variety of normal, reactive, and neoplastic epithelial tissues. The antibody reacts with simple, cornifying, and non-cornifying squamous epithelia and pseudostratified epithelia.
产品属性
形式
Liquid
存储溶液
Ascites
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
免疫原种属
Human
免疫原
cytokeratin from human epidermis.
纯化方式
Unpurified
偶联
Unconjugated
RRID
AB_385223
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
功能与背景
Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratin 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. PCK-26 facilitates the typing of normal, metaplastic and neoplastic cells and it may aid in the discrimination of carcinomas and non-epithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micro-metastases in lymph nodes and other tissues and for determining the origin of poorly differentiated tumors (1,2).
研究领域
產品图片
![Anti-pan Cytokeratin antibody [PCK-26] used in Western Blot (WB). GTX26401](/templates/default/js/lightbox/images/loading.gif "Anti-pan Cytokeratin antibody [PCK-26] used in Western Blot (WB). GTX26401")
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GTX26401 WB Image
WB analysis of HeLa cell lysate using GTX26401 pan Cytokeratin antibody[PCK-26].
Lane 1 : Antibody dilution 1:300
Lane 2 : Antibody dilution 1:500
Lane 3 : Antibody dilution 1:1000.
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GTX26401 IHC-P Image
IHC-P analysis of human placenta sections using GTX26401 pan Cytokeratin antibody [PCK-26] at 1:300.
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文献引用
产品评论
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![Anti-pan Cytokeratin antibody [PCK-26] used in Western Blot (WB). GTX26401](/upload/website/prouct_img/small/GTX26401/GTX26401_20170605_WB_w_23060722_268.webp "Anti-pan Cytokeratin antibody [PCK-26] used in Western Blot (WB). GTX26401")
![Anti-pan Cytokeratin antibody [PCK-26] used in IHC (Paraffin sections) (IHC-P). GTX26401](/upload/website/prouct_img/small/GTX26401/GTX26401_20170605_IHC-P_w_23060722_827.webp "Anti-pan Cytokeratin antibody [PCK-26] used in IHC (Paraffin sections) (IHC-P). GTX26401")
![Anti-pan Cytokeratin antibody [PCK-26] used in Western Blot (WB). GTX26401](/upload/website/prouct_img/normal/GTX26401/GTX26401_20170605_WB_w_23060722_268.webp "Anti-pan Cytokeratin antibody [PCK-26] used in Western Blot (WB). GTX26401")
![Anti-pan Cytokeratin antibody [PCK-26] used in IHC (Paraffin sections) (IHC-P). GTX26401](/upload/website/prouct_img/normal/GTX26401/GTX26401_20170605_IHC-P_w_23060722_827.webp "Anti-pan Cytokeratin antibody [PCK-26] used in IHC (Paraffin sections) (IHC-P). GTX26401")
