产品应用
应用说明
*最佳稀释倍数与浓度应由研究人员确认
| 实验应用 |
稀释倍数 |
| 1:500-1:3000 |
| Assay dependent |
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片
预期分子量
产品属性
形式
Liquid
存储溶液
PBS
存放说明
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
1 mg/ml (Please refer to the vial label for the specific concentration.)
免疫原种属
Human
免疫原
Recombinant fragment of human uPAR.
纯化方式
Affinity purified by Protein A.
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
plasminogen activator, urokinase receptor , CD87 , U-PAR , UPAR , URKR
细胞定位
Cell membrane,Secreted
功能与背景
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
数据库
研究领域
產品图片
![Anti-uPAR antibody [HL2398] used in Western Blot (WB). GTX638615](/templates/default/js/lightbox/images/loading.gif "Anti-uPAR antibody [HL2398] used in Western Blot (WB). GTX638615")
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GTX638615 WB Image
Wild-type (WT) and PLAUR knockout (KO) HeLa cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with uPAR antibody [HL2398] (GTX638615) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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GTX638615 IHC-P Image
uPAR antibody [HL2398] detects uPAR protein at cell membrane by immunohistochemical analysis.Sample: Paraffin-embedded human lung cancer.uPAR stained by uPAR antibody [HL2398] (GTX638615) diluted at 1:100.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX638615 IHC-P Image
uPAR antibody [HL2398] detects uPAR protein by immunohistochemical analysis.Sample: Paraffin-embedded mouse tissues.uPAR stained by uPAR antibody [HL2398] (GTX638615) diluted at 1:100.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX638615 WB Image
Untreated (–) and treated (+) U937 whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with uPAR antibody [HL2398] (GTX638615) diluted at 1:250. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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文献引用
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产品评论
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![Anti-uPAR antibody [HL2398] used in Western Blot (WB). GTX638615](/upload/website/prouct_img/small/GTX638615/GTX638615_T-45054_20230630_WB_KO_watermark_23062718_340.webp "Anti-uPAR antibody [HL2398] used in Western Blot (WB). GTX638615")
![Anti-uPAR antibody [HL2398] used in IHC (Paraffin sections) (IHC-P). GTX638615](/upload/website/prouct_img/small/GTX638615/GTX638615_T-45054_20230928_IHC-P_23102401_134.webp "Anti-uPAR antibody [HL2398] used in IHC (Paraffin sections) (IHC-P). GTX638615")
![Anti-uPAR antibody [HL2398] used in IHC (Paraffin sections) (IHC-P). GTX638615](/upload/website/prouct_img/small/GTX638615/GTX638615_T-45054_20230928_IHC-P_multiple_M_23102401_285.webp "Anti-uPAR antibody [HL2398] used in IHC (Paraffin sections) (IHC-P). GTX638615")
![Anti-uPAR antibody [HL2398] used in Western Blot (WB). GTX638615](/upload/website/prouct_img/small/GTX638615/GTX638615_45138_20230818_WB_treatment_PMA_23082201_284.webp "Anti-uPAR antibody [HL2398] used in Western Blot (WB). GTX638615")
![Anti-uPAR antibody [HL2398] used in Western Blot (WB). GTX638615](/upload/website/prouct_img/normal/GTX638615/GTX638615_T-45054_20230630_WB_KO_watermark_23062718_340.webp "Anti-uPAR antibody [HL2398] used in Western Blot (WB). GTX638615")
![Anti-uPAR antibody [HL2398] used in IHC (Paraffin sections) (IHC-P). GTX638615](/upload/website/prouct_img/normal/GTX638615/GTX638615_T-45054_20230928_IHC-P_23102401_134.webp "Anti-uPAR antibody [HL2398] used in IHC (Paraffin sections) (IHC-P). GTX638615")
![Anti-uPAR antibody [HL2398] used in IHC (Paraffin sections) (IHC-P). GTX638615](/upload/website/prouct_img/normal/GTX638615/GTX638615_T-45054_20230928_IHC-P_multiple_M_23102401_285.webp "Anti-uPAR antibody [HL2398] used in IHC (Paraffin sections) (IHC-P). GTX638615")
![Anti-uPAR antibody [HL2398] used in Western Blot (WB). GTX638615](/upload/website/prouct_img/normal/GTX638615/GTX638615_45138_20230818_WB_treatment_PMA_23082201_284.webp "Anti-uPAR antibody [HL2398] used in Western Blot (WB). GTX638615")
