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肿瘤代谢研究

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肿瘤代谢研究

Cancer Metabolism

Nearly a century ago, Otto Warburg found that cancer cells can shift their energy production to aerobic glycolysis instead of the more efficient oxidative phosphorylation. An emerging hallmark of many cancers is their metabolic plasticity, as rewiring of cancer cells' metabolic fluxes is essential for their proliferative and invasive agenda. With increasing understanding of these alterations, researchers are identifying features of tumor metabolism that can be used for novel diagnostic, prognostic, and therapeutic opportunities.

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IDH1 antibody

IDH1 antibody
(GTX629818)

IDH2 antibody

IDH2 antibody
(GTX628487)

LDHA antibody

LDHA antibody
(GTX101416)

Hexokinase 1 antibody

Hexokinase 1 antibody
(GTX105248)

PKM antibody

PKM antibody
(GTX107977)

Pyruvate Dehydrogenase E1 alpha antibody

Pyruvate Dehydrogenase E1 alpha antibody (GTX104015)

Pyruvate Dehydrogenase E1 beta subunit antibody

Pyruvate Dehydrogenase E1 beta subunit antibody (GTX104040)

SDHB antibody

SDHB antibody
(GTX104628)

Glutaminase C antibody

Glutaminase C antibody
(GTX131263)

Arginase 1 antibody

Arginase 1 antibody
(GTX109242)

Monoglyceride lipase antibody

Monoglyceride lipase antibody (GTX103517)

Fatty Acid Synthase antibody

Fatty Acid Synthase antibody (GTX109833)

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Article Alert: Acquired Resistance to Immunotherapy is Mediated by EMT and Irf6 Repression in Pancreatic Ductal Adenocarcinoma

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六码一抗不分包装～全面EXTRA 5% OFF！

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Article Alert: Stromal Monoamine Oxidase B Drives Prostate Cancer

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Download the latest version of GeneTex's The Tumor Microenvironment (TME) - Part 2 poster.

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Download the latest version of GeneTex's The Tumor Microenvironment (TME) - Part 1 poster.

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IFNγ刺激的KAT8-IRF1凝聚体可激活PD-L1表达并促进免疫逃逸

IFNγ-stimulated KAT8-IRF1 Condensates Activate PD-L1 Expression and Promote Immune Evasion

PARPs as Therapeutic Targets in Clinical Oncology

PARPs as Therapeutic Targets in Clinical Oncology

抑制HCK以增加免疫治疗的效果与用途

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由肿瘤微环境寻找髓母细胞瘤潜力新疗法-C3a受体与TNF-α受体拮抗剂

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内质网

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Epithelial–mesenchymal transition (EMT) Pathway

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Article Alert: Acquired Resistance to Immunotherapy is Mediated by EMT and Irf6 Repression in Pancreatic Ductal Adenocarcinoma

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Article Alert: Stromal Monoamine Oxidase B Drives Prostate Cancer

Article Alert: IFNγ-stimulated KAT8-IRF1 Condensates Activate PD-L1 Expression and Promote Immune Evasion

IFNγ刺激的KAT8-IRF1凝聚体可激活PD-L1表达并促进免疫逃逸

IFNγ-stimulated KAT8-IRF1 Condensates Activate PD-L1 Expression and Promote Immune Evasion

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抑制HCK以增加免疫治疗的效果与用途

抑制HCK以增加免疫治疗的效果与用途

由肿瘤微环境寻找髓母细胞瘤潜力新疗法-C3a受体与TNF-α受体拮抗剂

由肿瘤微环境寻找髓母细胞瘤潜力新疗法-C3a受体与TNF-α受体拮抗剂

ADAM17：人类疾病中的主要“脱落酶(Sheddase)”

ADAM17：人类疾病中的主要“脱落酶(Sheddase)”

ADAM17：人类疾病中的主要“脱落酶(Sheddase)”

内质网

内质网

内质网是由扁平的、相连的囊组成的真核膜细胞器，负责膜蛋白和分泌型蛋白的合成...

用于Omicron研究的抗体和重组蛋白

用于Omicron研究的抗体和重组蛋白

WHO将SARS-CoV-2变体B.1.1.529指定为第五种关注变体(VOC)，并将其命名为“Omicron”...

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NEK7：NLRP3 炎性小体激活的重要调节剂

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癌症研究冉冉升起的新星

类固醇生成急性调节蛋白 1 (StAR/StARD1) 介导类固醇生成中胆固醇从线粒体外膜转运到线粒体内膜的限速步骤...

雄激素受体（AR-V7 剪接变体特异性）抗体

雄激素受体（AR-V7 剪接变体特异性）抗体

在晚期前列腺癌中，雄激素受体剪接变体 7 (AR-V7) 是最丰富的雄激素受体 mRNA 剪接变体...

通过敲除验证的整合素 β-1抗体

通过敲除验证的整合素 β-1抗体

整合素是由α和β亚基组成的异二聚体蛋白，已在哺乳动物中发现了至少 18 个 α 亚基和 8 个 β 亚基...

NRF2激活的癌症治疗新范式

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NRF2激活的癌症治疗新范式

GeneTex推出SARS-CoV-2 (COVID-19) RBD ACE2结合活性/中和测定套组

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GeneTex推出SARS-CoV-2 (COVID-19) RBD ACE2结合活性/中和测定套组

Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

GeneTex推出RAS (G12D突变体) 重组抗体 [HL10]

GeneTex的RAS（G12D突变体）重组抗体适用于IHC染色和WB。

Clinical trials targeting alpha-synuclein protein in Parkinson’s disease

Clinical trials targeting alpha-synuclein protein in Parkinson’s disease

exosome PD-L1

Improving cancer immunotherapy efficacy may depend on targeting exosomes

Improving cancer immunotherapy efficacy may depend on targeting exosomes bearing the immune checkpoint protein PD-L1

「胶」你怎么做！Western blot省时小密技

六码一抗不分包装～全面EXTRA 5% OFF！

六码一抗不分包装～全面EXTRA 5% OFF！

GeneTex重组抗体试用计划

您发文献我送奖励 | 2024文献奖励方案

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