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Summary This antibody reacts exclusively with cytokeratin 18 which is present in glandular epithelial cells of the digestive, respiratory, and urogenital tracts, endocrine and exocrine cells and mesothelial cells, as well as adenocarcinomas originating from them.

Summary This antibody reacts to human CK-5 (Cytokeratin 5), and does not cross-react to CK-6 (Cytokeratin 6).

Summary Cross-reactivity was found with smooth muscle desmin.

Summary This antibody does not react with skeletal muscle or nerve cells.

Summary GTX74884 recognises the 200kD neurofilament protein in a range of species. The antibody stains various tumours including phaeochromocytoma, paraganglioma and ganglioneuroblastoma._x000B_It has also been demonstrated that GTX74884 also recognises a phosphorylation dependent epitope on microtubule associated protein 1B (MAP1B) and on Tau in Western blots. Reactivity of the antibody with MAP1B and Tau is not seen under the conditions for immunohistochemistry.