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Summary This antibody recognizes the Ly-6B.2 antigen in 129J; AKR; C57BL/6; C57BL/10; C58; DBA/2; NZB; NZW; SJL; MFI; Swiss (PO) Strains whilst A2G; A/Sn; ASW; BALB/c; C3H/HEH: CBA.T6T6 are negative or demonstrate very weak reactivity (Hirsch and Gordon 1982).

Summary The antibody MEM-75 does not block binding of transferrin to the receptor.

Summary Cross-reactivity with skeletal TnI is less than 10%.

Summary This antibody is specific for the approximately 95 kDa IR and shows no cross-reactivity with insulin like growth factor (IGF) receptors. Phosphorylation of the threonine residue within this sequence (corresponding to threonine 1348) decreases the affinity of this antibody for IR by approximately 100 fold. This antibody reacts with autophosphorylated IR, unoccupied IR, and the insulin IR complex. It has no effect on insulin-stimulated autophosphorylation.

Summary Reacts with free cardiac troponin I (cTnI). Reacts weakly with cTnI forming complexes with other troponin components.Not affected by phosphorylation. Recognizes an epitope located between amino acid residues 148 and 158 of cTnI. Nocross-reactivity with skeletal muscle troponin I.