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Summary Monoclonal antibody M81 reacts with an epitope on human C protein activated C1s, a subcomponent of the first component of C (C1). The epitope recognised by the antibody M81 is domain IV and/or V of the gamma-domain of activated C1s. Monoclonal antibody M81 blocks C4 activation and C4 binding to activated C1s. The antibody reacts around the binding site of C1s and reacts with both active and inactive C1s.

Summary Recognises the 85kDa cleaved fragment of Low Density LRP (extracellular domain).

Summary The antibody binds to soluble vitronectin as well as to membrane bound vitronectin.

Summary No cross-reaction with skeletal TnT.

Summary No cross-reactivity with skeletal muscle TnI.

Summary No cross-reactivity with skeletal muscle TnI.

Summary Cross-reactivity with skeletal TnI is less than 10%.

Summary Reacts with free cardiac troponin I (cTnI). Does not react with cTnI forming complexes with other troponincomponents. Not affected by phosphorylation. Recognizes an epitope between amino acid residues 65 and74 of cTnI. No crossreactivity with skeletal muscle cTnI. Reactive with cTnI from human, bovine, porcine,goat, canine, cat, rat and mouse.

Summary Reacts equally with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponincomponents. Not affected by heparin, phosphorylation and oxidation. Recognizes an epitope locatedbetween amino acid residues 26 and 35 of cTnI. No cross-reactivity with skeletal muscle troponin I.