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Summary Monoclonal Anti-vH RAS reacts with phosphorylated and non-phosphorylated forms of vH RAS and vK RAS p21's and reacts with the p21 transitional products of the H, K, and N ras human genes. It does not crossreact with Rap. This antibody neutralizes the activity of H, K, and NRas by binding to residues Glu-63, Ser-65, Ala-66, Met-67, Gln-70 and Arg-73.