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Summary P1W16 may be useful for prognosis of malignant melanoma.

Summary Reacts with reduced and non-reduced MMP-20. Recognizes the pro-form of MMP-20. Binds the propeptide region, which is removed during activation. Can be used to distinguish between the pro-form and active forms of MMP-20.

Summary Reacts with reduced and non-reduced MMP-19. Recognizes the pro-form and most active forms of MMP-19. The hemopexin domain is cleaved from the smallest active form of MMP-19 and the antibody does not detect this form.

Summary Reacts with reduced and non-reduced MMP-19. Recognizes the pro-form of MMP-19. Binds the propeptide region, which is removed during activation. Can be used to distinguish between the pro-form and active forms of MMP-19.

Summary Clone D8B7 is developed against the alpha II spectrin SH3 domain (Xu et al., 2001). Clone D8B7 is a specific marker for human, rat and mouse alpha II spectrin or fodrin. In cerebellar cell cultures, it labelsaxons and periphery of cell bodies consistent with localization of fodrin(reviewed in Bennett, 1993; Goodman, 1995 & De Matteis, 2000). It does notcrossreact with alpha I (erythroid) spectrin SH3 domain.