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Summary This antibody is able to detect native and recombinant human IL-23 and recognizes the p19 subunit of the IL-23 heterodimer (p40 + p19). In combination with MT86/221, it detects IL-23 heterodimer (p40 + p19) by sandwich ELISA.

Summary Clone 2F8 is unsuitable for use with the C57BL/6 mouse strain (Daugherty et al. 2000).

Summary Detects a monomorphic determinant on HLA-DR, a human Class II histocompatability antigen. Reacts with B lymphocytes, monocytes, macrophages, activated T cells, thymic epithelium, B cell dependent areas of spleen and lymph nodes, and B cell lymphomas. It inhibits T cell function at the clonal level.