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糖原生成和糖原分解

糖原生成和糖原分解

糖原生成和糖原分解

Glycogenolysis is the breakdown of glycogen branches through catabolic reactions via the sequential removal of glucose monomers via phosphorolysis, catalyzed by the enzyme glycogen phosphorylase. Glycogen is cleaved from glycogen (n) to produce glucose-1-phosphate and glycogen (n-1). Phosphoglucomutase (PGM) then converts glucose-1-phosphate into glucose-6-phosphate, which then enters the glycolytic pathway. Glycogenolysis takes place in muscle and liver cells in response to hormonal (i.e., glucagon, insulin, and epinephrine) and neural signals

Glycogenesis, in contrast, is the process of anabolic synthesis of glycogen. Glucose molecules are phosphorylated to glucose-6-phosphate, converted to glucose-1-phosphate and UDP-glucose, and added to glycogen chains for storage.

 

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文献引用 敲除敲弱策略 生物特性与正交策略

 

GPBB antibody(GTX104291)

GPBB antibody
(GTX104291)
Citation SupportOrthogonal Validation
PGM1 antibody(GTX110069)

PGM1 antibody
(GTX110069)
UGP2 antibody (GTX107967)

UGP2 antibody
(GTX107967)
Citation Support KOKD Validation
 
Glycogen synthase 1 antibody

Glycogen synthase 1 antibody
(GTX113453)
     

 

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