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Summary This antibody's epitope is resistant to digestion by trypsin and chymotrypsin.

Summary This antibody reacts with Class III epitope on CD34 (Mucosialin). The antibody 4H11[APG] completely blocks binding of Class II antibody QBEnd10 and Class III antibodies BIRMA K3 and 8G12 on KG1a cell line.

Summary This antibody reacts with Class II epitope on CD34 (Mucosialin). This antibody has been also used as an endothelial marker.
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Summary This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.