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肠病毒71型研究

肠病毒71型研究

Discovered in 1969, human enterovirus 71 (EV71) is the causative agent of hand-foot-and-mouth disease (HFMD) in young children, with a subset of patients developing more severe neurological disease that can result in death. Though epidemics have become more numerous since 1997, there are still no effective therapies or an established vaccine. Clearly, further research into the biology of this virus is of the utmost importance.
 
As a member of the genus Enterovirus in the family Picornaviridae, EV71 has a positive-stranded RNA genome coding for a 2,194 amino acid polyprotein, which is subsequently processed into four structural (VP1-VP4) and seven non-structural (2A, 2B, 2C, 3A, 3B, 3C, 3D) proteins. Identifying the specific functions of these proteins and their interactions with host factors will provide crucial information regarding EV71-associated neural pathogenesis and viral replication.
 
GeneTex is proud to offer an outstanding selection of antibodies for EV71 research. Please see the highlighted antibodies below or click here to see our latest EV71 research products.
 

Featured Products

 

Enterovirus 71 antibody (GTX124261)

WB analysis of EV71 proteins in RD cells infected with EV71 virus C2 or B4 strain.

Enterovirus 71 VP1 antibody (GTX132339)

WB analysis of EV71 VP1 protein in RD cells infected with EV71 virus C2 or B4 strain.

Enterovirus 71 3C antibody [B3] (GTX630191)

WB analysis of EV71 3C protein in RD cells infected with EV71 or EV D68 virus.
 

Enterovirus 71 3AB antibody (GTX132344)

IHC-P analysis detecting expression of EV71 3AB protein in an EV71 infected mouse skeletal muscle tissue section.

Enterovirus 71 2B antibody (GTX132343)

IHC-P analysis detecting expression of EV71 2B protein in an EV71 infected mouse skeletal muscle tissue section.

EV71 VP1 antibody (GTX132338)

IHC-P analysis detecting expression of EV71 VP1 protein in an EV71 infected mouse skeletal muscle tissue section.
 

 

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