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肿瘤标记

肿瘤标记

肿瘤标记是由癌细胞产生或诱导分泌的特定物质，可以在体内或肿瘤组织检测到，单一标志物或不同肿瘤标志物组合的鉴定，可以揭示特定癌症的存在与其阶段，并提供治疗后或长期治疗过程中的预后展望，下面的幻灯片视频，重点介绍了GeneTex针对不同癌症的一些肿瘤标记抗体，下表条列出了美国国家卫生研究院(NIH)认可的关键肿瘤标记与特定的GeneTex产品。

 

Table: Tumor markers listed by the NIH

Cat. No. Marker Tumor Type Sample Type
GTX81366 ALK Non-small cell lung cancer
Anaplastic large cell lymphoma		 Tumor tissue
GTX84954 Alpha-fetoprotein (AFP) Liver cancer
Germ cell tumors		 Blood
GTX34437 Beta-2-microglobulin (B2M) Multiple myeloma
Chronic lymphocytic leukemiaLymphomas		 Blood
Urine
Cerebrospinal fluid
GTX70111 BRCA1 Ovarian cancer
Breast cancer		 Blood
Tumor tissue
GTX70123 BRCA2 Ovarian cancer
Breast cancer		 Blood
Tumor tissue
GTX33595 BRAF V600 mutations Cutaneous melanoma
Erdheim-Chester disease
Colorectal cancer
Non-small cell lung cancer		 Tumor tissue
GTX11391 Beta hCG Choriocarcinoma
Germ cell tumors		 Blood
Urine
GTX01469 C-kit / CD117 Gastrointestinal stromal tumor
Mucosal melanoma		 Tumor tissue
GTX635388 CA19-9 Pancreatic cancer
Gallbladder cancer
Bile duct cancer
Gastric cancer		 Blood
GTX20697 CA-125 Ovarian cancer Blood
GTX17254 Carcinoembryonic antigen (CEA) Colorectal cancer
Some other cancers		 Blood
GTX100209 CD20 Non-Hodgkins lymphoma Blood
GTX113165 Chromogranin A (CgA) Neuroendocrine tumors Blood
GTX60766 EGFR mutations Non-small cell lung cancer Blood
GTX70174 Estrogen receptor (ER) Breast cancer Tumor tissue
GTX116051 Progesterone receptor (PR) Breast cancer Tumor tissue
GTX108640 Fibrin / fibrinogen Bladder cancer Urine
GTX20928 Gastrin Gastrin-producing tumors Blood
GTX01063 HE4 Ovarian cancer Blood
GTX100509 HER2 Breast cancer
Ovarian cancer
Bladder cancer
Pancreatic cancer
Stomach cancer		 Tumor tissue
GTX133076 IDH1 Acute myeloid leukemia Blood
Bone marrow
GTX628487 IDH2 Acute myeloid leukemia Blood
Bone marrow
GTX635362 RAS mutations Pancreatic cancer
Colorectal cancer
Non-small cell lung cancer		 Tumor tissue
GTX22101 Lactate dehydrogenase Germ cell tumors
Lymphoma
Leukemia
Melanoma
Neuroblastoma		 Blood
GTX133249 Neuron-specific enolase (NSE) Small cell lung cancer
Neuroblastoma		 Blood
GTX104763 Programmed death-ligand 1 (PD-L1) Non-small cell lung cancer
Liver cancer
Stomach cancer
Gastroesophageal junction cancer
Classical Hodgkins lymphoma
Other aggressive lymphoma subtypes		 Tumor tissue
GTX34989 Prostate-specific antigen (PSA) Prostate cancer Blood
GTX35115 Thyroglobulin Thyroid cancer Blood
GTX79597 Urokinase plasminogen activator (uPA) Breast cancer Tumor tissue
GTX60537 Plasminogen activator inhibitor (PAI-1) Breast cancer Tumor tissue

 

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