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CDH16 antibody [MSVA-516R] HistoMAX™

HistoMAX
Anti-CDH16 antibody [MSVA-516R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04455
Anti-CDH16 antibody [MSVA-516R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04455
Anti-CDH16 antibody [MSVA-516R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04455

Cat. No. GTX04455

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 MSVA-516R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($899),
100 μl ($299)
See all CDH16 products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48 and BOND RX - Leica. The detailed steps by Autostainer please refer to the protocol.
Not tested in other applications.

Calculated MW

90 kDa. ( Note )

Positive Control

Kidney: A strong staining should be seen in distal tubuli and collecting ducts while the staining is at least moderate in proximal tubuli.

Negative Control

Colon: All cells should be CDH16 negative.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human full-length CDH16 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cadherin 16

Cellular Localization

Cell membrane

Background

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]

Database

Research Area

DATA IMAGES

Anti-CDH16 antibody [MSVA-516R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04455

GTX04455 IHC-P Image

IHC-P analysis of human thyroid tissue section using GTX04455 CDH16 antibody [MSVA-516R] HistoMAX™.
CDH16 negative papillary carcinoma invading CDH16 positive normal thyroid CDH16 immunohistochemistry.

Anti-CDH16 antibody [MSVA-516R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04455

GTX04455 IHC-P Image

IHC-P analysis of human kidney chromophobe renal cell carcinoma tissue section using GTX04455 CDH16 antibody [MSVA-516R] HistoMAX™.
Chromophobe renal cell carcinoma with strong CDH16 immunostaining of tumor cells CDH16 immunohistochemistry.

Anti-CDH16 antibody [MSVA-516R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04455

GTX04455 IHC-P Image

IHC-P analysis of human thyroid gland tissue section using GTX04455 CDH16 antibody [MSVA-516R] HistoMAX™.
Strong membranous CDH16 staining of follicle cells CDH16 immunohistochemistry.

REFERENCE

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REVIEW

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Package List Price ($)
$ 899
$ 299