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GP2 antibody [MSVA-475M] HistoMAX™

Orthogonal HistoMAX
Anti-GP2 antibody [MSVA-475M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04436
Anti-GP2 antibody [MSVA-475M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04436
Anti-GP2 antibody [MSVA-475M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04436

Cat. No. GTX04436

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MSVA-475M

Isotype

 IgG2c

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($679),
100 μl ($299)
See all GP2 products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

Positive Control

Pancreas: Acinar cells should show a strong immunostaining with apical predominance. Duodenum: Glandular cells of Brunner glands should show a weak to moderate GP2 positivity.

Negative Control

Colon: GP2 staining should be completely absent in glandular and stromal cells.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human GP2 protein (around aa 35-179)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glycoprotein 2 , ZAP75

Cellular Localization

Cell membrane , Secreted

Background

This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Database

Research Area

DATA IMAGES

Anti-GP2 antibody [MSVA-475M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04436

GTX04436 IHC-P Image

IHC-P analysis of human pancreas tissue section using GTX04436 GP2 antibody [MSVA-475M] HistoMAX™.

Anti-GP2 antibody [MSVA-475M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04436

GTX04436 IHC-P Image

IHC-P analysis of human pancreatic acinar cell carcinoma tissue section using GTX04436 GP2 antibody [MSVA-475M] HistoMAX™.
Acinar cell carcinoma showing strong GP 2 immunostaining of all tumor cells.

Anti-GP2 antibody [MSVA-475M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04436

GTX04436 IHC-P Image

IHC-P analysis of human rectum mucosa tissue section using GTX04436 GP2 antibody [MSVA-475M] HistoMAX™.
GP2 immunostaining is completely lacking in rectal mucosa.

REFERENCE

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REVIEW

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Package List Price ($)
$ 679
$ 299