GeneTex中国官方网站
  • China

CD80抗体 [MEM-233]

目录号 GTX75761

文献引用 18

宿主

 Mouse

克隆

 Monoclonal

克隆编号

 MEM-233

同种型

 IgG1

实验应用

 WB, FACS, IP

种属反应

 Human, Monkey
产品包装
200 μg (¥6500)
查看所有 CD80 的产品

产品应用

应用说明

*最佳稀释倍数与浓度应由研究人员确认
实验应用 稀释倍数
WB Assay dependent
FACS Assay dependent
IP Assay dependent
WB: 免疫印迹
ICC/IF: 细胞染色
IHC-P: 石蜡切片
IHC-Fr: 冰冻切片

预期分子量

33 kDa. ( Note )

产品说明

This antibody binds to residues within the Ig-v-like domain of human CD80 as shown by domain switching studies (Vasu et al. 2003).

产品属性

形式

Liquid

存储溶液

PBS

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

浓度

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

免疫原种属

Human

纯化方式

Protein A purified

偶联

Unconjugated

RRID

AB_377015

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

相关讯息

别名

CD80 molecule , B7 , B7-1 , B7.1 , BB1 , CD28LG , CD28LG1 , LAB7

细胞定位

Membrane; Single-pass type I membrane protein

功能与背景

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]

数据库

研究领域

文献引用

Application Reference

Manferdini C et al. Biology (Basel) 2020; 9 (12) Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis.
Paolella F et al. J Cell Physiol 2018; (Epub) Effect of microfragmented adipose tissue on osteoarthritic synovial macrophage factors.
实验应用 : FACS
种属反应 : Human
Manferdini C et al. Arthritis Res Ther 2016; 18 (1) : 83 From osteoarthritic synovium to synovial-derived cells characterization: synovial macrophages are key effector cells.
实验应用 : FACS
种属反应 : Human

Clone Reference

Hovden AO et al. PLoS One 2012; 7 (2):e31217 The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner.
实验应用 : FACS
种属反应 : Human
Silk KM et al. Gene Ther 2012; 19 (10):1035-40 Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
显示更多 +
我要回报文献

产品评论

目前没有使用 CD80 antibody [MEM-233] (GTX75761) 的产品评论被收录。快发表第一篇产品评论吧！
我要评论产品
Application Reference
Manferdini C et al. Biology (Basel) 2020; 9 (12) Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis.
Paolella F et al. J Cell Physiol 2018; (Epub) Effect of microfragmented adipose tissue on osteoarthritic synovial macrophage factors.
实验应用 : FACS
种属反应 : Human
Manferdini C et al. Arthritis Res Ther 2016; 18 (1):83 From osteoarthritic synovium to synovial-derived cells characterization: synovial macrophages are key effector cells.
实验应用 : FACS
种属反应 : Human
Clone Reference
Silk KM et al. J Biomed Biotechnol 2012; 2012:172420 Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype.
实验应用 : FACS
种属反应 : Human
Hovden AO et al. PLoS One 2012; 7 (2):e31217 The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner.
实验应用 : FACS
种属反应 : Human
Silk KM et al. Gene Ther 2012; 19 (10):1035-40 Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
Hovden AO et al. BMC Immunol 2011; 12:2 Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses.
Piconi S et al. J Immunol 2010; 185 (12):7723-30 Immunological effects of sublingual immunotherapy: clinical efficacy is associated with modulation of programmed cell death ligand 1, IL-10, and IgG4.
Trojan J et al. Biomed Pharmacother 2010; 64 (8):576-8 Antisense anti IGF-I cellular therapy of malignant tumours: immune response in cancer patients.
John J et al. BMC Immunol 2010; 11:14 differential effects of * on dendritic cell function.
实验应用 : FACS
Daubenberger CA et al. Vet Immunol Immunopathol 2007; 119 (43102):14-20 Flow cytometric analysis on cross-reactivity of human-specific CD monoclonal antibodies with splenocytes of Aotus nancymaae, a non-human primate model for biomedical research.
实验应用 : FACS
种属反应 : Monkey
Newman KC et al. PLoS Pathog 2006; 2 (12):e118 cross-talk with myeloid accessory cells regulates human natural killer cell *-gamma responses to malaria.
实验应用 : FACS
Angel CE et al. J Immunol 2006; 176 (10):1398971 Cutting edge: CD1a+ antigen-presenting cells in human dermis respond rapidly to CCR7 ligands.
实验应用 : FACS
Tan PH et al. Blood 2005; 105 (10):3824-32 Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy.
实验应用 : FACS
Huxley P et al. Chem Biol 2004; 11 (12):1651-8 High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy.
Tan PH et al. Atherosclerosis 2004; 173 (2):171-83 Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells.
Zhan H et al. Invest Ophthalmol Vis Sci 2003; 44 (9):732951 The immunomodulatory role of human conjunctival epithelial cells.
实验应用 : FACS
Scheinecker C et al. J Immunol 1998; 161 (8):3966-73 Initiation of the autologous mixed lymphocyte reaction requires the expression of costimulatory molecules B7-1 and B7-2 on human peripheral blood dendritic cells.
实验应用 : FACS
SDS
PBS.pdf
Sodium Azide.pdf
产品包装 报价 (¥)
¥ 6500
联系经销商
欣博盛生物科技有限公司
欣博盛生物科技有限公司
(全国热线) 4006-800-892 / (深圳) 0755-26755892 / (北京) 010-88594029 / (上海) 021-34613729 / (广州) 18024516375 / (香港) +852-69410778
http://www.neobioscience.com
genetex@neobioscience.com