形式
Lyophilized powder
存储溶液
Reconstitute in 20mM Tris, 150mM NaCl pH8.0 to a concentration of 0.1-1.0 mg/mL. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl pH8.0, 0.01% SKL, 5% Trehalose.
保存剂
No preservatives
存放说明
Store at -20ºC or below. After reconstitution, keep as concentrated solution. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
浓度
Batch dependent (Please refer to the vial label for the specific concentration.)
Region/Sequence
N-terminal His tagged full length human Lipocalin-2 protein (Gln21~Gly198: a signal peptide removed), Uniprot #P80188-1).
表达系统
293F cell
纯度
>90% by SDS-PAGE
内毒素
<1.0 EU/1μg
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
别名
lipocalin 2 , 24p3 , MSFI , NGAL , p25
细胞定位
Secreted
功能与背景
This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]
数据库
研究领域
