产品应用
应用说明
Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-Leu-Arg-AMC. The IC₅₀ value is < 15 nM.
Observed MW
48 kDa.
产品属性
形式
Lyophilized powder
存储溶液
Batch dependent (please contact us for details)
存放说明
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Region/Sequence
C-terminal polyhistidine tag; Met1-Ile436 (NP_076178.1)
表达系统
Baculovirus-Insect Cells
纯度
> 90 % by SDS-PAGE.
内毒素
< 1.0 EU/μg (determined by LAL method)
偶联
Unconjugated
注意事项
仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
相关讯息
别名
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3 , 2900045C01Rik , AI428471 , mKIAA4039
功能与背景
This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
数据库
研究领域
產品图片
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GTX03578-pro Image
SDS-PAGE of GTX03578-pro mouse SPOCK3 protein, His tag (active).
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文献引用
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产品评论
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