Von Hippel Lindau 抗体对

目录号 GTX500022

实验应用	ELISA, Sandwich ELISA
种属反应	Human
产品包装	1 pair (¥4700)

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说明书

View product citations for antibody GTX500022 on CiteAb

产品说明

Product Content

GTX101087

Type : Capture Antibody

宿主 : Rabbit

偶联 : Unconjugated

产品包装 : 50 μl

GTX89268

Type : Detection Antibody

宿主 : Goat

偶联 : Unconjugated

产品包装 : 50 μl

产品应用

应用说明

We recommend using the capture antibody at a concentration of 2.5μg/mL and the detection antibody at a concentration of 1.5μg/mL. Optimal dilutions should be determined experimentally by the researcher.

产品属性

形式

Liquid

存放说明

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

注意事项

仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。

别名

Von Hippel-Lindau Tumor Suppressor , Hrca1 , Rca1 , Vhl1 , Pvhl , Vhl

功能与背景

Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]

研究领域

產品图片

GTX500022 ELISA Image

ELISA detection of VHL using GTX101087 for capture at a concentration of 2.5 μg/mL and GTX89268 for detection at a concentration of 1.5 μg/mL. The HRP-conjugated anti-goat IgG antibody (GTX26741) was diluted at 1:20,000-1:200,000 and used to detect the primary antibody.

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产品包装

报价 (¥)

1 pair

¥ 4700

Qty

Von Hippel Lindau 抗体对

目录号 GTX500022

实验应用

种属反应